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61747

N-Lauroylsarcosine sodium salt solution

30% aqueous solution, ≥97.0% (HPLC)

Synonym(s):

Sarcosyl, Sarkosyl NL, Sodium N-dodecanoyl-N-methylglycinate, Sodium N-lauroylsarcosinate solution

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About This Item

Linear Formula:
CH3(CH2)10CON(CH3)CH2COONa
CAS Number:
137-16-6
Molecular Weight:
293.38
UNSPSC Code:
12161902
NACRES:
NA.25
PubChem Substance ID:
57651864
MDL number:
MFCD00042728
Beilstein/REAXYS Number:
5322974
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description

anionic

Quality Level

200

assay

≥97.0% (HPLC)

form

liquid

quality

30% aqueous solution

mol wt

average mol wt 600

aggregation number

2

technique(s)

protein quantification: suitable

pH

7.0-9.0 (25 °C)

CMC

14.6

solubility

water: soluble at 20 °C (soluble)

density

1.033 g/mL at 20 °C

cation traces

Ca: ≤20 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤10 mg/kg, K: ≤70 mg/kg, Mg: ≤10 mg/kg, Mn: ≤5 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

SMILES string

[Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O

InChI

1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1

InChI key

KSAVQLQVUXSOCR-UHFFFAOYSA-M

Application

N-Lauroylsarcosine (Sarcosyl) is an ionic surfactant useful in a wide range of solubilization and permeation applications from solubilization of membrane proteins to enhancement of skin permeability in transdermal applications.

Other Notes

Solubilization of membrane proteins; useful for rupturing of eukaryote cells in transcription studies; In the lysis of Clostridium perfringens for rapid extraction of plasmids

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ppe

Eyeshields, Gloves

pictograms

Exclamation mark
GHS07

wgk

WGK 1

signalword

Warning

hcodes

H319,H332

Hazard Classifications

Acute Tox. 4 Inhalation - Eye Irrit. 2

Storage Class

10 - Combustible liquids

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Certificates of Analysis (COA)

Lot/Batch Number
1380393
451336/1
442197/1
437221/1
436882/1

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H Wroblewski et al.
Biochimie, 60(4), 389-398 (1978-01-01)
1. Up to 90 per cent of the membrane proteins from Spiroplasma citri could be solubilized with the anionic detergent Sarkosyl (sodium lauroyl-sarcosinate). Maximal solubilization was obtained with 6 to 20 mumoles of of detergent per mg of membrane protein.
Properties of the polyoma virus transcription complex obtained from mouse nuclei.
R J Shmookler et al.
Virology, 57(1), 122-127 (1974-01-01)
D E Mahony et al.
Applied and environmental microbiology, 51(3), 521-523 (1986-03-01)
Two rapid methods were evaluated for their extraction of plasmids from Clostridium perfringens. The first method involved lysis of 1 to 2 ml of C. perfringens culture by treatment with hyaluronidase, lysozyme, and sarcosyl. DNA, extracted with phenol-chloroform, was treated
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Global Trade Item Number

SKUGTIN
61747-100ML04061832700632
61747-500ML04061832700649