45698
Trichlorfon
PESTANAL®, analytical standard
Synonym(s):
(2,2,2-Trichloro-1-hydroxyethyl)phosphonic acid dimethyl ester, Metrifonate
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About This Item
Empirical Formula (Hill Notation):
C4H8Cl3O4P
CAS Number:
Molecular Weight:
257.44
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-149-3
Beilstein/REAXYS Number:
1709434
MDL number:
grade
analytical standard
Quality Level
product line
PESTANAL®
shelf life
limited shelf life, expiry date on the label
application(s)
agriculture
environmental
format
neat
storage temp.
2-8°C
SMILES string
COP(=O)(OC)C(O)C(Cl)(Cl)Cl
InChI
1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3
InChI key
NFACJZMKEDPNKN-UHFFFAOYSA-N
Biochem/physiol Actions
Trichlorfon also known as metrifonate, is an insecticide that functions as an inhibitor of acetylcholine esterase. Trichlorfon has been shown to induce DNA damage and genetic defects in numerous cell lines in addition to inducing aneuploidy in male mouse germ cells.
Legal Information
PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
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signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Resp. Sens. 1 - Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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F Y Sun et al.
Mutagenesis, 15(1), 17-24 (2000-01-21)
In order to assess the effects of trichlorfon on cell division and on aneuploidy induction, we conducted an in vitro assay for spindle disturbances using V79 cells and an in vivo assay for aneuploidy induction in meiosis of male mice
Sónia Coelho et al.
Aquatic toxicology (Amsterdam, Netherlands), 103(3-4), 191-198 (2011-04-09)
Trichlorfon (TCF) is one of the most used veterinary pharmaceuticals not only to fight infestations but also as a preventive measure worldwide. The high concentrations used generate concerns about environmental and human health. In this work we assessed the acute
G M Wang et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 27(7), 983-988 (2010-05-01)
Trichlorfon is a thermally unstable insecticide that can be easily decomposed to dichlorvos at high temperatures. In this study, a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for simultaneous determination of the residues of trichlorfon and dichlorvos in animal
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 45698-250MG-R | 04061832341804 |
| 45698-50MG-R | 04061832341811 |