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MilliporeSigma

30461

Sigma-Aldrich

DEAE-Dextran hydrochloride

BioReagent, Molecular Biology

Synonym(s):

Diethylaminoethyl-dextran hydrochloride

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.25
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grade

Molecular Biology

Quality Level

product line

BioReagent

form

solid

impurities

DNases, none detected
RNases, none detected
phosphatases, none detected
proteases, none detected

solubility

H2O: 0.1 g/mL, clear

storage temp.

room temp

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Application

DEAE-Dextran, a polycationic stabilizing molecule and transfection reagent, is used in the development of sustained release protein delivery and nucleic acid transfection systems.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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S Tabor et al.
Current protocols in immunology, Chapter 10, Unit 10-Unit 10 (2008-04-25)
Extensive knowledge of the enzymology involved in biosynthesis and degradation of nucleic acids has permitted the development of simple methods for labeling RNA and DNA with radioisotopes or biotin. These labeled probes are used primarily for hybridization to nucleic acid
Transfection using DEAE-dextran.
Gulick T.
Current Protocols in Cell Biology, doi: 10-doi: 10 (2003)
J Zarate et al.
Journal of microencapsulation, 28(7), 614-620 (2011-07-12)
Bovine serum albumin (BSA) loaded calcium alginate microparticles (MPs) produced in this study by a w/o emulsification and external gelation method exhibited spherical and fairly smooth and porous morphology with 1.052 ± 0.057 µm modal particle size. The high permeability of the calcium
DEAE-dextran transfection of lymphocyte cell lines.
Smale ST.
Cold Spring Harbor Protocols, doi: 10-doi: 10 (2010)
Shingo Kikuchi et al.
International journal of pharmaceutics, 386(1-2), 149-155 (2009-11-20)
A multivariate statistical technique was applied to designing a tablet for the sustained release over 24h of diltiazem hydrochloride, a model highly water-soluble drug. Tablets of a hydrophilic matrix composed of dextran derivatives and hypromellose were prepared. The formulations were

Related Content

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

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