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MilliporeSigma

24370C

SAFC

EX-CELL® Advanced HD Perfusion Medium

powder

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About This Item

UNSPSC Code:
12352200

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Quality Level

500

product line

EX-CELL®

form

dry powder

technique(s)

cell culture | mammalian: suitable (suspension)

shipped in

ambient

storage temp.

2-8°C

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General description

EX-CELL® Advanced HD Perfusion Medium is chemically-defined and contains no animal derived components. The new medium has been specifically developed to support growth and productivity across a diverse set of Chinese Hamster Ovary (CHO) cells in perfusion cultures while still allowing for flexibility in the adjustment of protein quality attributes. This medium was developed using a strategy of Multivariate Analysis to establish correlations in which the formulation components influence critical process and product attributes such as titer, fold expansion, protein expression and glycosylation. This medium is intended to be used in perfusion processes. While the medium was developed specifically for steady-state perfusion, it can also support other perfusion applications such as N-1, continuous fed-batch and production perfusion where cells are not bled.

Preparation Note

Formulated to contain 28.57 grams of powder per liter of medium.

Legal Information

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

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GHS07

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Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
RNBM0935
RNBM0288
RNBL8182
RNBL4002
RNBK8394

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Articles

CHO Media and Feeds for Optimized Production of Therapeutic Proteins

Cellvento® and EX-CELL® CHO cell culture media and feeds, optimized for monoclonal antibody & recombinant protein production in fed-batch & perfusion

Establishing the First GMP Guideline for Cell Culture Media

Cell culture media are vital for bioprocessing therapeutics. This page describes the central role of our organization in authoring purpose-built GMP for cell culture media.

Building Regional Cell Culture Media Supply Chains

Ensure reliable cell culture media supply with our continuously expanding global network of regional sites for resilient biopharma manufacturing.

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Product Information Sheet - 24370C
Accelerate development and optimization of cell culture media for upstream perfusion processes

This page describes the use of a small-scale perfusion bioreactor with integrated microfluidic flow control and sensor technologies to predict large-scale processes.

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