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MilliporeSigma

24366C

SAFC

EX-CELL® Advanced CHO Fed-batch Medium

powder

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.71

Key Documents

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Quality Level

500

product line

EX-CELL®

form

dry powder

technique(s)

cell culture | mammalian: suitable (suspension)

shipped in

ambient

storage temp.

2-8°C

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General description

EX-CELL® AdvancedCHO Fed-batch Medium is chemically-defined and contains no animal derived components. This newest platform from SAFC has been specifically developed to support growth and productivity across a diverse set of Chinese Hamster Ovary (CHO) cells in fed-batch cultures while still allowing for flexibility in the adjustment of protein quality attributes. This contemporary fed-batch platform was developed using a strategy of Multivariate Analysis to establish correlations in which the formulation components influence critical process and product attributes such as titer, fold expansion, receptor expression, and glycosylation. This platform contains no hypoxanthine and thymidine, L-glutamine, phenol red or 2-mercaptoethanol (2-ME). This medium is intended to be a part of a fed-batch platform, and used with EX-CELL® Advanced CHO Feed 1 (24367C - with glucose or 24368C - without glucose).

Preparation Note

Formulated to contain 22.09 grams of powder per liter of medium.

Legal Information

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark
GHS07

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Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0001599814
0001580670
0001580669
0001580671
RNBL4950-A

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Articles

EX-CELL® Advanced™ CHO Fed-Batch System – Bioprocessing Technology Institute, Singapore Case Study

In this study, nine commercially available, chemically defined media and feed combinations from different vendors were assessed for producing monoclonal antibody in Chinese hamster ovary (CHO) cells.

Improving Fed-batch Yields in Upstream Bioprocessing

Our step-by-step guide to optimizing media and feed combinations for upstream bioprocessing.

Low-Impurity Iron Sources: Case Studies in EX-CELL® Advanced Medium

Discover how low-impurity iron sources improve reliability and performance in recombinant protein production with EX-CELL® Advanced medium.

CHO Media and Feeds for Optimized Production of Therapeutic Proteins

Cellvento® and EX-CELL® CHO cell culture media and feeds, optimized for monoclonal antibody & recombinant protein production in fed-batch & perfusion

See All

Related Content

Cell Culture Media and Feeds Selection Guide
User Guide CHOZN GS Platform
EX-CELL Advanced CHO Fed-batch Medium Product Information Sheet
Glycosylation Modulation in Fed-batch Production of Therapeutic Proteins

Enhance mAb and recombinant protein performance, efficacy, and stability with precise glycosylation modulation using the Cellvento® ModiFeed platform.

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