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About This Item
Linear Formula:
CH3CON(CH3)2
CAS Number:
Molecular Weight:
87.12
UNSPSC Code:
12352111
NACRES:
NA.21
PubChem Substance ID:
EC Number:
204-826-4
Beilstein/REAXYS Number:
1737614
MDL number:
eCl@ss:
39031204
Assay:
99%
Bp:
164.5-166 °C (lit.)
Vapor pressure:
2 mmHg ( 25 °C), 4 mmHg ( 38 °C)
vapor density
3 (vs air)
Quality Level
vapor pressure
2 mmHg ( 25 °C), 4 mmHg ( 38 °C)
product line
ReagentPlus®
assay
99%
form
liquid
autoignition temp.
914 °F
expl. lim.
1.8 %, 100 °F, 11.5 %, 160 °F
dilution
(for general lab use)
refractive index
n20/D 1.437 (lit.)
pH
4 (20 °C, 200 g/L)
bp
164.5-166 °C (lit.)
mp
−20 °C (lit.)
density
0.937 g/mL at 25 °C (lit.)
SMILES string
CN(C)C(C)=O
InChI
1S/C4H9NO/c1-4(6)5(2)3/h1-3H3
InChI key
FXHOOIRPVKKKFG-UHFFFAOYSA-N
General description
N,N-Dimethylacetamide (DMAc) is a water-miscible organic solvent used in the synthesis of styrene′s, vinyl resins, linear polyesters, acrylic fibers, plastics, pesticides, and synthetic leather. Additionally, it is utilized in the production of adhesives, films, and paint. It participates in dehydrogenation, dehydration, halogenation, deprotonation reactions and reductive carbonylation of transition metals. It can also act as catalysts, promoters, halogen/alkoxy or hydroxyl/halogen exchange mediators, reducing agents, and sources of the base.
Application
N,N-Dimethylacetamide can be used as a solvent in the synthesis of:
It can also be used:
- Cellulose-HA (hydroxyapatite) nanocomposites using microcrystalline cellulose, CaCl2, and NaH2PO4.
- 5-hydroxymethylfurfural (HMF) from various carbohydrates and natural biopolymer lignocellulose in the presence of LiCl.
It can also be used:
- In the Pd-catalyzed regioselective synthesis of ketones from olefins using molecular oxygen.
- As a solvent as well as a methylene source in the regioselective linkage of two imidazo[1,2-a] pyridines using Cu(OAc)2 catalyst.
Features and Benefits
N,N-Dimethylacetamide has
- High dissolution power of various substrate.
- High capacity to solvate anions.
Legal Information
Belle Chemical Company
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Repr. 1B
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
flash_point_f
147.2 °F - closed cup
flash_point_c
64 °C - closed cup
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André H Gröschel et al.
Nature communications, 3, 710-710 (2012-03-20)
Hierarchical self-assembly offers elegant and energy-efficient bottom-up strategies for the structuring of complex materials. For block copolymers, the last decade witnessed great progress in diversifying the structural complexity of solution-based assemblies into multicompartment micelles. However, a general understanding of what
Fen Ran et al.
Acta biomaterialia, 7(9), 3370-3381 (2011-06-11)
An amphiphilic triblock co-polymer of poly(vinyl pyrrolidone)-b-poly(methyl methacrylate)-b-poly(vinyl pyrrolidone) (PVP-b-PMMA-b-PVP) was synthesized via reversible addition-fragmentation chain transfer (RAFT) polymerization. The block co-polymer can be directly blended with polyethersulfone (PES) using dimethylacetamide (DMAC) as the solvent to prepare flat sheet and
Agnieszka Partyka et al.
Theriogenology, 75(9), 1623-1629 (2011-03-15)
The aim of this study was to perform flow cytometric analysis of C11-BODIPY581/591 oxidation in fowl and geese sperm as a marker for membrane lipid peroxidation (LPO) and to establish if the cryopreservation process would make sperm membranes more susceptible
Global Trade Item Number
| SKU | GTIN |
|---|---|
| D137510-2.5L | 04061833559673 |
| D137510-4L | 04061833559680 |
| D137510-18L-CS | 04061837717000 |
| D137510-1L | 04061833559666 |
| D137510-20L | 04061837717017 |
| D137510-500ML | 04061837226977 |

