T7875

Thiourea

Name: Thiourea
Brand: SIAL

≥99.0%, ReagentPlus^®

Synonym(s):

Sulfourea, Thiocarbamide

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About This Item

Linear Formula:

NH₂CSNH₂

CAS Number:

62-56-6

Molecular Weight:

76.12

Beilstein/REAXYS Number:

605327

EC Number:

200-543-5

MDL number:

MFCD00008067

UNSPSC Code:

12352100

PubChem Substance ID:

57654702

NACRES:

NA.21

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Product Name

Thiourea, ReagentPlus^®, ≥99.0%

Quality Level

200

product line

ReagentPlus^®

assay

≥99.0%

mp

170-176 °C (lit.)

functional group

amine
thiourea

SMILES string

NC(N)=S

InChI

1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)

InChI key

UMGDCJDMYOKAJW-UHFFFAOYSA-N

Gene Information

mouse ... Ephx2(13850)

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Organic Building Blocks

General description

Thiourea is an analogue of urea, containing sulphur.

Application

Chaotropic agent; strong denaturant. Increases solubility and recovery of proteins

Thiourea has been used:

as a component in ice cold sample buffer for protein analysis
in intracellular extraction buffer for the extraction of soluble intracellular proteins
as a component of electrophoresis buffer

Biochem/physiol Actions

Thiourea is a free radical scavenger of the peroxide radical. It was shown to inhibit lipid peroxidation and ultraviolet (UV)-induced crosslinking of collagen. Bud dormancy in plants can be inhibited by thiourea, which is used as a growth stimulator. It is also known to be used in the treatment of hyperthyroidism.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

GHS08,GHS07,GHS09

signalword

Warning

hcodes

H302,H351,H361fd,H411

pcodes

P202 - P264 - P273 - P280 - P301 + P312 - P308 + P313

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Feline hypertrophic cardiomyopathy associated with the p. A31P Mutation in cMyBP-C is caused by production of mutated cMyBP-C with reduced binding to actin

Godiksen MTN, et al.

Open Journal of Veterinary Medicine, 3(02), 95-95 (2013)

Synergistic effects of glucose and ultraviolet irradiation on the physical properties of collagen

Ohan MP, et al.

Journal of Biomedical Materials Research, 60(3), 384-391 (2002)

Protocol: Optimised methodology for isolation of nuclei from leaves of species in the Solanaceae and Rosaceae families

Sikorskaite S, et al.

Plant methods, 9(1), 31-31 (2013)

Extraction of Intracellular and Cell Wall Proteins from Leaves and Roots of Harsh Hakea

Shane MW and Plaxton WC

Journal of Experimental Botany (2014)

Mechanism of the reduction of methylene blue by thiourea in aqueous acidic medium

Osunlaja AA

International Journal of ChemTech Research, 4(2), 609-617 (2012)

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Thiourea