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MilliporeSigma

D4911

Sigma-Aldrich

Dextran sulfate sodium salt from Leuconostoc spp.

mol wt 6,500-10,000

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About This Item

CAS Number:
9011-18-1
MDL number:
MFCD00081551
UNSPSC Code:
12352201
NACRES:
NA.21

Key Documents

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biological source

bacterial (Leuconostoc)

Quality Level

100

form

powder

mol wt

6,500-10,000

composition

Sulfur Content, 16.0-22.0%

color

white to light yellow

useful pH range

6.0-8 (10 g/L)

solubility

H2O: 100 mg/mL

storage temp.

room temp

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General description

Dextran sulfate is a sulfated polysaccharide, which is negatively charged. It is produced by the esterification of dextran with chlorosulphonic acid. Dextran is used to treat hemorrhage, burns, surgery and trauma. It improves blood flow and prevents erythrocyte aggregation. Dextran lowers the risk of thrombosis and postoperative pulmonary emboli. It is a ribonuclease inhibitor. Dextran sulfate exhibits antiviral, anticoagulant and adjuvant properties.

Application

Dextran sulfate sodium salt Leuconostoc spp has been used:
  • as a standard to perform polyacrylamide-gel electrophoresis for carbohydrates (C-PAGE)(59) and agarose gel electrophoresis(60)
  • for RNA sequential probing of targets (SPOTs) imaging(61)
  • as a component of 1% injection buffer(62)

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKCQ7650
MKCP8993
MKCP8992
MKCP8615
MKCN8616

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Radiotherapy, Surgery, and Immunotherapy (2012)
Structural features and anticancer activity in vitro of fucoidan derivatives from brown alga Saccharina cichorioides
Anastyuk SD, et al.
Carbohydrate Polymers, 157, 1503-1510 (2017)
Radiotherapy, Surgery, and Immunotherapy (2012)
Jinsung Hong et al.
Biotechnology progress, 35(5), e2831-e2831 (2019-05-03)
An alternating tangential flow (ATF) perfusion-based transient gene expression (TGE) bioprocess has been developed using human embryonic kidney (HEK) 293 cells to produce H1-ss-np, a promising candidate for a universal influenza vaccine. Two major adjustments were taken to improve the
Rheology of Industrial Polysaccharides: Theory and Applications (2012)
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Protocols

Dextran Sulfate

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

Related Content

Dextran and Polysaccharides Overview

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

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