biological source
bacterial (Leuconostoc)
Quality Level
form
powder
mol wt
6,500-10,000 by GPC
composition
Sulfur Content, 16.0-22.0%
color
white to light yellow
useful pH range
6.0-8 (10 g/L)
solubility
H2O: 100 mg/mL
storage temp.
room temp
General description
Dextran sulfate is a sulfated polysaccharide, which is negatively charged. It is produced by the esterification of dextran with chlorosulphonic acid. Dextran is used to treat hemorrhage, burns, surgery and trauma. It improves blood flow and prevents erythrocyte aggregation. Dextran lowers the risk of thrombosis and postoperative pulmonary emboli. It is a ribonuclease inhibitor. Dextran sulfate exhibits antiviral, anticoagulant and adjuvant properties.
Application
Dextran sulfate sodium salt Leuconostoc spp has been used:
- as a standard to perform polyacrylamide-gel electrophoresis for carbohydrates (C-PAGE)(59) and agarose gel electrophoresis(60)
- for RNA sequential probing of targets (SPOTs) imaging(61)
- as a component of 1% injection buffer(62)
Other Notes
To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.
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Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Protocols
Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.
Related Content
Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.
Radiotherapy, Surgery, and Immunotherapy (2012)
Structural features and anticancer activity in vitro of fucoidan derivatives from brown alga Saccharina cichorioides
Anastyuk SD, et al.
Carbohydrate Polymers, 157, 1503-1510 (2017)
Radiotherapy, Surgery, and Immunotherapy (2012)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| D4911-10G | 04061833033098 |
| D4911-100G | 04061833033081 |
| D4911-1G | 04061833585856 |
| D4911-50G | 04061833585863 |