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MilliporeSigma

31579

Supelco

Androsterone

VETRANAL®, analytical standard

Synonym(s):

3α-Hydroxy-5α-androstan-17-one, 5α-Androstan-3α-ol-17-one

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About This Item

Empirical Formula (Hill Notation):
C19H30O2
CAS Number:
Molecular Weight:
290.44
Beilstein/REAXYS Number:
2217626
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
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grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

181-184 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

[H][C@@]12CC[C@@]3([H])[C@]4([H])CCC(=O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CC[C@@H](O)C2

InChI

1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12-16,20H,3-11H2,1-2H3/t12-,13+,14-,15-,16-,18-,19-/m0/s1

InChI key

QGXBDMJGAMFCBF-HLUDHZFRSA-N

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General description

Androsterone is a tetracydic compound which forms mono-esters or mono-oxime with one hydroxyl group and one keto group respectively.

Application

Androsterone has been used as working reference standard in identifying natural androgen steroids using liquid chromatography–tandem mass spectrometry (LC–MS–MS) in multiple reaction monitoring (MRM) from bovine and urine samples.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard

signalword

Danger

Hazard Classifications

Carc. 2 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Development of a liquid chromatography?tandem mass spectrometry method for the identification of natural androgen steroids and their conjugates in urine samples.
Buiarelli, F., et al.
Analytica Chimica Acta, 526.2, 113-120 (2004)
Herbert J Tobias et al.
Drug testing and analysis, 10(4), 781-785 (2017-09-30)
High-precision carbon isotope ratio analysis of urinary steroids by gas chromatography-combustion-isotope ratio mass spectrometry (GC-C-IRMS) is the official test to detect illicit doping of synthetic versions of endogenous steroids, such as testosterone. Our group created the first steroid isotopic standards
Michael Polet et al.
Drug testing and analysis, 11(11-12), 1656-1665 (2019-04-23)
Steroid detection and identification remain key issues in toxicology, drug testing, medical diagnostics, food safety control, and doping control. In this study, we evaluate the capabilities and usefulness of analyzing non-hydrolyzed sulfated steroids with gas chromatography-mass spectrometry (GC-MS) instead of
Amelia Palermo et al.
Analytica chimica acta, 964, 112-122 (2017-03-30)
The urinary steroidal fraction has been extensively explored as non-invasive alternative to monitor pathological conditions as well as to unveil the illicit intake of pseudo-endogenous anabolic steroids in sport. However, the majority of previous approaches involved the a priori selection
Subrata Deb et al.
Cancers, 10(10) (2018-09-23)
Castration-resistant prostate tumors acquire the independent capacity to generate androgens by upregulating steroidogenic enzymes or using steroid precursors produced by the adrenal glands for continued growth and sustainability. The formation of steroids was measured by liquid chromatography-mass spectrometry in LNCaP

Articles

Los sistemas de producción de agua ultrapura Milli-Q® suministran agua exenta de contaminantes orgánicos, incluidas las hormonas presentes en el agua del grifo de un laboratorio, lo que los hace adecuados para los análisis mediante LC-MS/MS más sensibles.

Milli-Q® ultrapure water systems deliver water free of organic contaminants , including hormones present in a lab's tap water, making it suitable for the most sensitive LC-MS/MS analyses.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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