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12-0880

L-Glutamic acid

Name: <SC>L</SC>-Glutamic acid
Brand: SAJ

JIS special grade, ≥99.0%

Synonym(s):

(S)-2-Aminopentanedioic acid, Glu

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About This Item

Linear Formula:

HO₂CCH₂CH₂CH(NH₂)CO₂H

CAS Number:

56-86-0

Molecular Weight:

147.13

EC Number:

200-293-7

UNSPSC Code:

12352116

PubChem Substance ID:

329749615

Beilstein/REAXYS Number:

1723801

MDL number:

MFCD00002634

Assay:

≥99.0%

Form:

crystalline

Grade:

JIS special grade

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Properties

grade

JIS special grade

assay

≥99.0%

form

crystalline

availability

available only in Japan

mp

205 °C (dec.) (lit.)

solubility

water: soluble 8.64 g/L at 25 °C

density

1.54 g/cm³ at 20 °C

application(s)

peptide synthesis

SMILES string

N[C@@H](CCC(O)=O)C(O)=O

InChI

1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1

InChI key

WHUUTDBJXJRKMK-VKHMYHEASA-N

Description

Biochem/physiol Actions

An excitatory amino acid neurotransmitter that is an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA).

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Relationships between glutamate and monoamine metabolites in cerebrospinal fluid and serum in healthy volunteers.

G Alfredsson et al.

Biological psychiatry, 23(7), 689-697 (1988-04-01)

The concentrations of homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA), 4-hydroxy-3-methoxyphenylglycol (HMPG), and glutamate were determined in cerebrospinal fluid (CSF) and serum in 10 healthy volunteers. The monoamine metabolites were measured by mass fragmentography and the glutamate by high-performance liquid chromatography.

Molecular mechanisms and therapeutical implications of intramembrane receptor/receptor interactions among heptahelical receptors with examples from the striatopallidal GABA neurons.

Luigi F Agnati et al.

Pharmacological reviews, 55(3), 509-550 (2003-07-19)

The molecular basis for the known intramembrane receptor/receptor interactions among G protein-coupled receptors was postulated to be heteromerization based on receptor subtype-specific interactions between different types of receptor homomers. The discovery of GABAB heterodimers started this field rapidly followed by

Glutamate, substance P, and calcitonin gene-related peptide cooperate in inflammation-induced heat hyperalgesia.

Katarzyna Rogoz et al.

Molecular pharmacology, 85(2), 322-334 (2013-11-28)

The transient receptor potential cation channel subfamily V member 1 (TRPV1) is known as a thermosensor and integrator of inflammation-induced hyperalgesia. TRPV1 is expressed in a subpopulation of primary afferent neurons that express several different neurotransmitters. The role of the

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Global Trade Item Number

SKU	GTIN
12-0880-5-500G-J	04061832684505
12-0880-2-25G-J	04061832684499