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MilliporeSigma

SKBM02560

PES Membrane Filter

Strat-M®

Synonym(s):

PES membrane for transdermal diffusion testing, Polyethersulfone Strat-M membrane, Strat-M® Membrane, Transdermal Diffusion Test Model, 25mm

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About This Item

UNSPSC Code:
40161507
NACRES:
NB.24
eCl@ss:
32160907
Material:
plain filter, polyethersulfone membrane (synthetic lipid post-treatment), polyolefin membrane (synthetic lipid post-treatment), white filter
Diam.:
25 mm
Sterility:
non-sterile
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Quality Level

material

plain filter, polyethersulfone membrane (synthetic lipid post-treatment), polyolefin membrane (synthetic lipid post-treatment), white filter

sterility

non-sterile

manufacturer/tradename

Millipore, Strat-M®

diam.

25 mm

filter diam.

25 mm

thickness

300 μm

shipped in

ambient

General description

Filter Code: SKBM
Strat-M Membrane for Transdermal Diffusion Testing
Experience the unmatched predictability of Strat-M membrane – a synthetic, non-animal based model for transdermal diffusion testing that is predictive of diffusion in human skin without lot-to-lot variability, safety and storage limitations.

Strat-M membrane is designed for screening of:
•Active pharmaceutical ingredients (API)
•Cosmetic actives
•Formulations
•Personal care products
•Pesticides and chemicals

Human Skin Correlation
Strat-M membrane is predictive of diffusion in human skin for a wide range of compounds and formulations. Use the Compound Correlation Tool to learn how well Strat-M membrane will work for you.

Reproducible Diffusion Data:
No need to repeat testing each time a new lot of skin arrives in the lab. Strat-M membrane is a highly consistent, engineered material that allows you to compare today’s diffusion data with data you will generate next week, or next month. Furthermore, lot-to-lot consistency brings a new level of clarity to your test data, simplifying your analysis.

Sensitive to Enhancers
Strat-M membrane exhibits differential permeability in the presence of enhancers and is compatible with common formulation formats, so it is appropriate for use during formulation optimization.

Ultimate Experimental Convenience
Strat-M membrane was designed with convenience in mind. The Strat-M membrane is shelf-stable and stocked in the warehouse so procurement and storage is a breeze. Each membrane is individually packaged as precut discs and do not need to be hydrated prior to use. Simply remove the Strat-M membrane disc from its pouch and load into a Franz cell.

Application

Strat-M membrane is a synthetic, non-animal based model for transdermal diffusion testing that is predictive of diffusion in human skin without lot-to-lot variability, safety & storage limitations.

Legal Information

STRAT-M is a registered trademark of Merck KGaA, Darmstadt, Germany


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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Protocols

Strat-M® synthetic membrane mimics the human skin for In-vitro permeation testing (IVPT) of topical and transdermal formulations

Step-by-step protocol and video for transdermal diffusion testing using Strat-M® synthetic skin membranes.

Articles

Strat-M synthetic membrane model is an alternative to human skin for testing the effectiveness of skin care actives.

Related Content

Strat-M® membrane offers consistent transdermal diffusion testing, ensuring reliable data for comparative analysis over time.


PREDICTION OF SKIN PERMEATION BY CHEMICAL COMPOUNDS USING THE ARTIFICIAL MEMBRANE, STRAT-M?
Uchida T, Kadhum WR, Kanai S, Todo H, Oshizaka T, Sugibayashi K
European Journal of Pharmaceutical Sciences null
IN VITRO SKIN MODELS AS A TOOL IN OPTIMIZATION OF DRUG FORMULATION.
Flaten GE, Palac Z, Engesland A, Filipovic-Grcic J, Vanic Z, Skalko-Basnet N
European Journal of Pharmaceutical Sciences null
IMPACT OF DIFFERENT VEHICLES FOR LASER-ASSISTED DRUG PERMEATION VIA SKIN: FULL-SURFACE VERSUS FRACTIONAL ABLATION.
Lee WR, Shen SC, Aljuffali IA, Li YC, Fang JY.
Pharmaceutical Research null



Global Trade Item Number

SKUGTIN
SKBM0256004053252649851