PC150
Anti-β-Amyloid (1-42) Rabbit pAb
liquid, Calbiochem®
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
biological source
rabbit
Quality Level
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
liquid
does not contain
preservative
species reactivity
human
packaging
antibody small pack of 25 μg
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
dilution
(Dot Blot (0.1-0.5 µg/mL)
ELISA (0.1-0.5 µg/mL)
Radioimmunoassay (0.5 µg/mL))
isotype
IgG
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... APP(351)
Related Categories
General description
Rabbit polyclonal antibody adsorbed against Aβ1-40 and Aβ1-43, followed by immunoaffinity purification. Recognizes specifically β-amyloid peptide (1-42).
Recognizes specifically β-amyloid peptide (1-42). Does not cross-react with β-amyloid peptide (1-40) or β-amyloid peptide (1-43).
- Antibody Target Gene Symbol: APP
- Target Synonym: AAA, AD1, Adap, AL024401, Amyloid precursor, Amyloidogenic glycoprotein, APP isoform 1, APPI, appican, CTFgamma, CVAP, E030013M08RIK, Nexin II, P3, PN2, PreA4, PROTEASE NEXIN2
- Entrez Gene Name: amyloid beta (A4) precursor protein
- Hu Entrez ID: 351 (Related Antibodies: 171610, PC729,PC152, PC151, PC149, NE1012, 171609, 171608, 171607, 171606, 171605, 171604, 171603, 171598, 171537)
- Mu Entrez ID: 11820
- Rat Entrez ID: 54226
This Anti-β-Amyloid (1-42) Rabbit pAb is validated for use in Dot Blot, ELISA, Radioimmunoassay for the detection of β-Amyloid (1-42).
Immunogen
Human
a synthetic peptide corresponding to amino acids from a C-terminal fragment of human β-amyloid peptide (1-42)
Application
Dot Blot (0.1-0.5 µg/ml)
ELISA (0.1-0.5 µg/ml)
Radioimmunoassay (0.5 µg/ml)
ELISA (0.1-0.5 µg/ml)
Radioimmunoassay (0.5 µg/ml)
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In phosphate buffer, pH 7.4.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Other Notes
Savage, M.J., et al. 1998. J. Neurosci.15, 1743.
Borchelt, D.R., et al. 1997. Neuron19, 939.
Citron, M., et al. 1997. Nature Med.3, 67.
Hardy, J. 1997. Trends in Neurosci.20, 154.
Solomon, B., et al. 1997. Proc. Natl. Acad. Sci. USA94, 4109.
Duff, K., et al. 1996. Nature383, 710.
Iwatsubo, T., et al. 1994. Neuron13, 45.
Suzuki, N., et al. 1994. Science264, 133.
Borchelt, D.R., et al. 1997. Neuron19, 939.
Citron, M., et al. 1997. Nature Med.3, 67.
Hardy, J. 1997. Trends in Neurosci.20, 154.
Solomon, B., et al. 1997. Proc. Natl. Acad. Sci. USA94, 4109.
Duff, K., et al. 1996. Nature383, 710.
Iwatsubo, T., et al. 1994. Neuron13, 45.
Suzuki, N., et al. 1994. Science264, 133.
This antibody is specific for β-amyloid peptide [1-42] and shows no reactivity to β-amyloid peptide [1-40] or β-amyloid peptide [1-43]. This antibody is recommended for use in the quantitative determination of β-amyloid peptide [1-42]. The sensitivity level for sandwich ELISA is 15-25 pg. Antibody should be titrated for optimal results in individual systems.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
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Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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