MILLIPLEX^® Mouse Aging Panel 1

Biomarkers such as CTACK/CCL27, FGF-21, GnRH, IL-6, Jag1, Leptin, Notch1, and TNFα are central to understanding the biological processes of aging in mouse models. CTACK/CCL27 is involved in skin-associated immune signaling, while FGF-21 regulates metabolic adaptation and longevity. GnRH controls reproductive aging, and IL-6 and TNFα are key inflammatory cytokines linked to age-related immune dysregulation. Jag1 and Notch1 are part of the Notch signaling pathway, which influences cellular differentiation and tissue regeneration. Leptin reflects changes in energy balance and adipose tissue function. Together, these analytes provide a comprehensive view of molecular aging and systemic decline.

MILLIPLEX^® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 8 analytes in mouse serum, plasma, or cell culture supernatants.

Analytes included: CTACK/CCL27, FGF-21, GnRH, IL-6, Jag1, Leptin, Notch1, TNFα

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Features:

• Measures key aging-related biomarkers involved in immune regulation, metabolism, and cellular signaling
• Includes CTACK/CCL27, FGF-21, GnRH, IL-6, Jag1, Leptin, Notch1, and TNFα
• Multiplex format allows simultaneous detection of multiple analytes from minimal sample volume
• Compatible with mouse serum, plasma, and tissue culture supernatant samples
• Designed for aging, longevity, and age-related disease research in preclinical models

Benefits:

• Provides a comprehensive molecular profile of aging processes in mice
• Supports investigation of age-associated inflammation, metabolic shifts, and reproductive decline
• Facilitates evaluation of anti-aging therapies and interventions
• Enhances understanding of Notch and FGF signaling pathways in tissue regeneration and aging
• Streamlines experimental workflows with high-throughput, multi-analyte capability

Luminex is a registered trademark of Luminex Corporation

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.