Skip to Content
MilliporeSigma

48-612MAG

MILLIPLEX® Akt/mTOR Signaling Panel

Premixed Akt/mTOR Total 11-Plex Cell Signaling Panel

Synonym(s):

Magnetic bead assay, Akt mTOR total assay, Akt total protein, PI3K pathway assay, kinase total assay, mTOR total detection, multiplex total ELISA, total protein panel, total signaling proteins

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

NACRES:
NA.47
UNSPSC Code:
12161503
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


Product Name

MILLIPLEX® Akt/mTOR Signaling Panel,

Quality Level

description

Premixed Akt/mTOR Total 11-Plex Cell Signaling Panel

species reactivity

human

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

technique(s)

multiplexing: suitable

input

cell lysate

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

This panel targets total expression of key proteins in the PI3K/Akt/mTOR signaling pathway, which regulates cell growth, metabolism, and survival. It includes total levels of Akt isoforms, mTOR, PTEN, GSK3α/β, IRS1, IGF1R, IR, p70S6K, and RPS6. These proteins are frequently altered in cancer, diabetes, and neurodegenerative diseases.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 11 analytes in human, mouse, or rat cell lysate samples.

Analytes Included: Akt (Total), GSK3α (Total), GSK3β (Total), IGF-1R (Total), IR (total), IRS1 (Total), mTOR (Total), p70S6K (Total), PTEN (Total), RPS6 (Total), TSC2 (Total)

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmateControl Assays).

Features and Benefits

  • Simultaneously detect total expression of 11 proteins in the PI3K/Akt/mTOR signaling pathway
  • Includes Akt1, Akt2, Akt3, mTOR, PTEN, GSK3α/β, IRS1, IGF1R, IR, p70S6K, and RPS6
  • Magnetic bead-based format ensures reproducibility and efficient processing
  • Compatible with cell lysates from cancer, metabolic, and signaling studies
  • Ideal for oncology, metabolism, and cell biology research
  • Fast, convenient alternative to Western Blotting and immunoprecipitation procedures

Legal Information

Luminex is a registered trademark of Luminex Corporation
MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.


Still not finding the right product?


pictograms

Exclamation mark

Storage Class

10-13 - German Storage Class 10 to 13

signalword

Danger

Hazard Classifications

Aquatic Chronic 3 - ED ENV 1 - Eye Irrit. 2

wgk

WGK 2



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library


Related Content

Find protein research tools to prepare, isolate, and analyze proteins. Organized by how to extract, protect, purify, enrich, modify, and quantify proteins.

View All Related Content




Global Trade Item Number

SKUGTIN
48-612MAG04053252757518