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MilliporeSigma

137666

SAFC

Ethylene glycol

EMPROVE® EVOLVE

Synonym(s):

Ethylene Glycol Emprove® Evolve, 1,2-Ethanediol

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About This Item

Linear Formula:
HOCH2CH2OH
CAS Number:
107-21-1
Molecular Weight:
62.07
Beilstein/REAXYS Number:
505945
MDL number:
MFCD00002885
UNSPSC Code:
12352137

Key Documents

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agency

CIP (cleaning in place)

Quality Level

400

vapor density

2.1 (vs air)

vapor pressure

0.053 hPa ( 20 °C)
0.08 mmHg ( 20 °C)

product line

EMPROVE® EVOLVE

assay

≥99.5% (GC)

form

liquid

autoignition temp.

410 °C
752 °F

expl. lim.

15.3 %
3.2-15.3 %

impurities

≤0.00002% Chloride (CI)
≤0.001% Acidity (as CH3COOH)

refractive index

n20/D 1.431 (lit.)

pH

6-7.5 (20 °C, 100 g/L)

bp

195-198 °C
197.6 °C/1013 hPa

mp

-14--10 °C
−13 °C (lit.)

transition temp

flash point 111 °C

density

1.11 g/cm3 at 20 °C
1.113 g/mL at 25 °C (lit.)

application(s)

pharma/biopharma processes

storage temp.

2-30°C

SMILES string

OCCO

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

Related Categories

General description

The new Ehtylene Glycol Emprove® Evolve meets the increasing quality requirements of of the biopharma industry for cleaning and storage of protein A resin.
We offer a range of high quality critical raw materials plus the documentation and expertise to help our customers meet stringent regulatory requirements. Our SAFC® portfolio of high-quality products withstands strict quality control procedures.

Application

Ethylene Glycol EMPROVE® Evolve meets the increasing quality requirements of the biopharma industry for cleaning and storage of protein A resin in downstream processes.
This chemical is used in the downstream process for the cleaning and storage of protein A resin.

Features and Benefits

Ethylene Glycol Emprove® Evolve cleaning and storage chemical can increase the lifetime of our Eshmuno® A resin as well as other protein A resins.

Packaging

Packsizes:
  • 1376661000: 1 L
  • 1376669025: 25 L
  • 1376669950: 950 L

Other Notes

More than 100% increase in column lifetime was achieved using a mixture of 20 % Ethylene Glycol and 0.1M NaOH solution. As a comparison, using traditional 0.1M solution resulted in an 80 % drop after just 250 cycles compared to an impressive 600 cycles using Ethylene Glycol Emprove® Evolve and 0.1M NaOH solution.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
Eshmuno is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation markHealth hazard
GHS07,GHS08

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - STOT RE 2 Oral

target_organs

Kidney

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

239.0 °F - open cup

flash_point_c

115 °C - open cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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