Key Documents

View All Documentation

1.04219

Guanidinium chloride

Name: Guanidinium chloride
Brand: MM

for biochemistry

Synonym(s):

Guanidine hydrochloride, Guanidinum hydrochloride, Carbamimidoylazanium chloride, Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, Guanidinium chloride

Select a Size

Change View

About This Item

Linear Formula:

NH₂C(=NH)NH₂ · HCl

CAS Number:

50-01-1

Molecular Weight:

95.53

EC Index Number:

200-002-3

UNSPSC Code:

12352107

Beilstein/REAXYS Number:

3591990

MDL number:

MFCD00013026

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Quality Level

100

potency

655.3-907.1 mg/kg LD₅₀, oral (Rat), >2000 mg/kg LD₅₀, skin (Rabbit)

pH

4.5-5.5 (20 °C, 100 g/L in H₂O)

mp

180-185 °C (lit.)

density

1.3 g/cm³ (lit.)

bulk density

550‑620 kg/m³

storage temp.

2-30°C

SMILES string

Cl[H].NC(N)=N

InChI

1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H

InChI key

PJJJBBJSCAKJQF-UHFFFAOYSA-N

Description

General description

Biological detergent
Agent for reversible denaturation of proteins. Special grade with low optical density for use in procedures where spectrometry is involved.

Application

Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.

Analysis Note

Assay (Perchloric acid titration, calc. on anhydrous substance): ≥ 99.5 %
Identity (IR-spectrum): passes test
pH (100 g/l, water): 5.5 - 6.5
Melting point: 183 - 188 °C
Absorbance A (235 nm; 50 %; 1 cm; water): ≤ 0,2
Heavy metals (as Pb): ≤ 10 ppm
Fe (Iron): ≤ 5 ppm
Sulfated ash (600 °C): ≤ 0.05 %
Water (according to Karl Fischer): ≤ 1

Still not finding the right product?

Explore all of our products under Guanidinium chloride

pictograms

GHS07

signalword

Warning

pcodes

P261 - P264 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_c

Not applicable

flash_point_f