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MilliporeSigma

906840

Poly(L-lactide-co-caprolactone)

lactide:caprolactone 90:10, viscosity 1.7 dL/g 

Synonym(s):

PCL-PLLA, PLLA-PCL

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About This Item

Linear Formula:
CH3(C6H10O2)m(C6H8O4)nCH3
UNSPSC Code:
12162002
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form

chunks

feed ratio

lactide:caprolactone 90:10

color

white to off-white

viscosity

1.7 dL/g

storage temp.

−20°C

General description

Poly(L-lactide-co-caprolactone) (PCL-PLLA) is a biodegradable polymer which can be synthesized by bulk ring-opening copolymerization of L-lactide and ε-caprolactone. Its properties include flexibility, biocompatibility and controlled degradation process.

Application

Poly(L-lactide-co-caprolactone) (PLLA-PCL) is a biodegradable copolymer. poly(L-lactide) exhibits a high modulus and has been often copolymerized with PCL to improve the mechanical properties of PCL, and increase degradation rate of the resulting polymer. PLLA-PCL has been used in tissue engineering, 3D bioprinting and drug delivery research applications.
PCL-PLLA can be used for a variety of applications such as tissue engineering, bone fixation devices and surgical sutures.


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Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Comparison of plasma and chemical modifications of poly-L-lactide-co-caprolactone scaffolds for heparin conjugation
Hsieh Y, et al.
Bio-medical materials and engineering, 12(6), 065004-065004 (2017)
Preclinical animal study and human clinical trial data of co-electrospun poly (L-lactide-co-caprolactone) and fibrinogen mesh for anterior pelvic floor reconstruction
Wu X, et al.
International journal of nanomedicine, 11(6), 389-389 (2016)
Fabrication and characterization of vitamin B5 loaded poly (l-lactide-co-caprolactone)/silk fiber aligned electrospun nanofibers for schwann cell proliferation
Bhutto MA, et al.
Colloids and Surfaces. B, Biointerfaces, 144(6), 108-117 (2016)



Global Trade Item Number

SKUGTIN
906840-5G04054839937309