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779873

Methyl-β-cyclodextrin

Name: Methyl-β-cyclodextrin
Brand: ALDRICH

Wacker Chemie AG, ≥98.0% cyclodextrin basis

Synonym(s):

Cavasol^® W7 M Life Science, MβCD, Methyl-beta-cyclodextrin

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About This Item

CAS Number:

128446-36-6

MDL number:

MFCD00066764

UNSPSC Code:

12352201

NACRES:

NA.22

Assay:

≥98.0% cyclodextrin basis

Form:

powder

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Properties

Quality Level

200

assay

≥98.0% cyclodextrin basis

form

powder

optical activity

[α]/D 154.0 to 156.0°

mol wt

M_w 1310 g/mol

manufacturer/tradename

Wacker Chemie AG

extent of labeling

1.7-1.9 molar substitution

impurities

≤0.10% unsubstituted cyclodextrin, ≤0.20% chloride, ≤0.50% reducing substances, ≤50 ppm volatile organics

ign. residue

≤0.50%

loss

≤5.0% loss on drying

color

white to off-white

mp

180-182 °C (lit.)

absorption

≤0.10 at 350-600 nm in solution at 10%, ≤1.00 at 220-350 nm in solution at 10%

SMILES string

O1C2OC(C(OC3OC(C(OC4OC(C(OC5OC(C(OC6OC(C(OC7OC(C(OC8OC(C1C(C8OC)O)COC)C(C7OC)O)COC)C(C6OC)O)COC)C(C5OC)O)COC)C(C4OC)O)COC)C(C3OC)O)COC)C(C2OC)O)COC

InChI

1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3

InChI key

QGKBSGBYSPTPKJ-UHFFFAOYSA-N

Description

Application

Methyl-β-cyclodextrin is a macrocyclic compound that can form inclusion complexes with a number of guest molecules. It shows higher solubility in aqueous solutions and greater solubilizing and complexing power compared to the parent β-cyclodextrin. MβCD can be used to enhance the enzyme activity and enantioselectivity of subtilisin enzyme in organic solvents.

Other Notes

For R&D Use

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Legal Information

Cavasol is a registered trademark of Wacker Chemie AG

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

368.6 °F

flash_point_c

187 °C

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Preparation and solid-state characterization of inclusion complexes formed between miconazole and methyl-?-cyclodextrin.

Ribeiro A

Aaps Pharmscitech, 9(4), 1102-1109 (2008)

Improved enzyme activity and enantioselectivity in organic solvents by methyl-?-cyclodextrin.

Griebenow K

Journal of the American Chemical Society, 121(36), 8157-8163 (1999)

Desmosterol can replace cholesterol in sustaining cell proliferation and regulating the SREBP pathway in a sterol-Delta24-reductase-deficient cell line.

Sara Rodríguez-Acebes et al.

The Biochemical journal, 420(2), 305-315 (2009-03-06)

Cholesterol homoeostasis is critical for cell viability and proliferation. The SREBP (sterol regulatory element-binding protein) pathway is crucial for the maintenance of cholesterol homoeostasis. This pathway is controlled by cholesterol and cholesterol-derived oxysterols. J774 cells cannot convert desmosterol into cholesterol

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Global Trade Item Number

SKU	GTIN
779873-100G	04061833301685
779873-10KG	04061833381397
779873-500G	04061833552384