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725692

Poly(ethylene glycol) dimethacrylate

average MN 20,000, cross-linking reagent polymerization reactions, methacrylate, ≤1, 500 ppm MEHQ as inhibitor (may contain)

Synonym(s):

Polyethylene glycol, PEG dimethacrylate

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About This Item

Linear Formula:
C3H5C(O)(OCH2CH2)nOC(O)C3H5
CAS Number:
25852-47-5
NACRES:
NA.23
UNSPSC Code:
12162002
MDL number:
MFCD00081877
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Product Name

Poly(ethylene glycol) dimethacrylate, average Mn 20,000, contains MEHQ as inhibitor

form

powder

mol wt

average Mn 20,000

contains

MEHQ as inhibitor, ≤1,500 ppm MEHQ as inhibitor (may contain)

reaction suitability

reagent type: cross-linking reagent
reaction type: Polymerization Reactions

bp

>200 °C/2 mmHg (lit.)

transition temp

Tm 59-64 °C

Mw/Mn

≤1.1

Ω-end

methacrylate

α-end

methacrylate

polymer architecture

shape: linear
functionality: homobifunctional

storage temp.

−20°C

SMILES string

OCCO.CC(=C)C(O)=O

InChI

1S/C10H14O4/c1-7(2)9(11)13-5-6-14-10(12)8(3)4/h1,3,5-6H2,2,4H3

InChI key

STVZJERGLQHEKB-UHFFFAOYSA-N

Preparation Note

Synthesized with an initial concentration of ≤1,500 ppm MEHQ

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Storage Class

11 - Combustible Solids

wgk

WGK 1

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Articles

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Injectable Hydrogels for Tissue Regeneration

Hydrogel-based biomaterials for cell delivery and tissue regeneration applications are discussed.

Patterning PEG-based Hydrogels for Complexity

Scaffold patterning with poly(ethylene glycol)-based hydrogels for cell presence in 2D and 3D environments on photoactive substrates.

Hailuo Fu et al.
Materials science & engineering. C, Materials for biological applications, 33(4), 2245-2250 (2013-03-19)
Implants that simultaneously function as an osteoconductive matrix and as a device for local drug or growth factor delivery could provide an attractive system for bone regeneration. In our previous work, we prepared hollow hydroxyapatite (abbreviated HA) microspheres with a
Sophia W Liao et al.
Biomaterials, 34(16), 3984-3991 (2013-03-08)
Islet transplantation offers a promising treatment for type 1 diabetes (T1D). However, a major hurdle in this treatment is the rapid loss of functional islets during culture and after transplantation. The liver site, currently utilized for transplantation, is suboptimal for
Pelagie M Favi et al.
Materials science & engineering. C, Materials for biological applications, 33(4), 1935-1944 (2013-03-19)
The culture of multipotent mesenchymal stem cells on natural biopolymers holds great promise for treatments of connective tissue disorders such as osteoarthritis. The safety and performance of such therapies relies on the systematic in vitro evaluation of the developed stem
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Global Trade Item Number

SKUGTIN
725692-1G04061826742044