Skip to Content
MilliporeSigma

Key Documents

View All Documentation

430471

Poly(D,L-lactide-co-glycolide)

ester terminated, Mw 50,000-75,000

Synonym(s):

Lactel® B6006-1, PLGA

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Linear Formula:
[C3H4O2]x[C2H2O2]y
UNSPSC Code:
12162002
PubChem Substance ID:
24866924
NACRES:
NA.23
MDL number:
MFCD00131930
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Level

100

form

amorphous

feed ratio

lactide:glycolide 85:15

mol wt

Mw 50,000-75,000

degradation timeframe

<6 months

viscosity

0.55-0.75 dL/g, 0.1 % (w/v) in chloroform(25 °C)

transition temp

Tg 45-50 °C

solubility

ethyl acetate, chloroform, acetone and THF: soluble

storage temp.

2-8°C

SMILES string

OCC(O)=O.CC(O)C(O)=O

InChI

1S/C3H6O3.C2H4O3/c1-2(4)3(5)6;3-1-2(4)5/h2,4H,1H3,(H,5,6);3H,1H2,(H,4,5)

InChI key

XBBVURRQGJPTHH-UHFFFAOYSA-N

General description

Characteristic properties of ester terminated poly(D,L-lactide-co-glycolide) (PLGA) are in vivo biodegradability, tunable drug release profile and very high encapsulation capacity.

Application

PLGA polymers find uses in the production of biodegradable medical sutures and for controlled drug release. PLGA microspheres have been reported for use in controlled release of human growth hormone. Thin membranes of blended polymers constituting of PLGA/polycaprolactone/β-tricalcium phosphate have been used in guided bone regeneration.

Features and Benefits

Controlled release of bioactive agents, sutures and bioabsorbable implantable devices.

Physical form

Biocompatible, biodegradable polymer.

Legal Information

Lactel is a registered trademark of Evonik Corp

Still not finding the right product?

Explore all of our products under Poly(D,L-lactide-co-glycolide)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
49597MJ
47697LJ
01308EJ
20020CH
19920CH

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Bioprinting for Tissue Engineering and Regenerative Medicine

In the past two decades, tissue engineering and regenerative medicine have become important interdisciplinary fields that span biology, chemistry, engineering, and medicine.

Biodegradable Aliphatic Polyesters for Drug Delivery

Innovations in polymer technology have had a significant impact on the advancement of novel drug delivery systems.

Biodegradable Polyester Nanoparticle Formation

AliAliphatic polyesters, including polylactide and polyglycolide, are biodegradable polymers widely used in medical applications.

View All Articles
Preparation and characterization of poly (D, L-lactide-co-glycolide) microspheres for controlled release of human growth hormone
Capan Y, et al.
Aaps Pharmscitech, 4(2), 147-156 (2003)
Fabrication of blended polycaprolactone/poly (lactic-co-glycolic acid)/?-tricalcium phosphate thin membrane using solid freeform fabrication technology for guided bone regeneration
Shim JH, et al.
Tissue Engineering: Part A, 19(3-4), 317-328 null
Manjae Gil et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 5(6), 1800024-1800024 (2018-06-26)
Anisotropically compartmentalized microparticles have attracted increasing interest in areas ranging from sensing, drug delivery, and catalysis to microactuators. Herein, a facile method is reported for the preparation of helically decorated microbuilding blocks, using a modified electrohydrodynamic cojetting method. Bicompartmental microfibers
View All Related Papers

Global Trade Item Number

SKUGTIN
430471-1G04061835563029
430471-5G04061835563036