Key Documents

View All Documentation

105902

p-Toluenesulfonamide

Name: <I>p</I>-Toluenesulfonamide
Brand: ALDRICH

reagent grade, 97%

Synonym(s):

4-Methylbenzene-1-sulfonamide, p-Tosylamide

Select a Size

Change View

About This Item

Linear Formula:

CH₃C₆H₄SO₂NH₂

CAS Number:

70-55-3

Molecular Weight:

171.22

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24846713

EC Number:

200-741-1

Beilstein/REAXYS Number:

472689

MDL number:

MFCD00011692

Assay:

97%

Form:

solid

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

grade

reagent grade

Quality Level

100

assay

97%

form

solid

mp

134-137 °C (lit.)

solubility

DMSO: soluble

functional group

sulfonamide

SMILES string

Cc1ccc(cc1)S(N)(=O)=O

InChI

1S/C7H9NO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3,(H2,8,9,10)

InChI key

LMYRWZFENFIFIT-UHFFFAOYSA-N

Gene Information

human ... CA1(759), CA2(760), CA5A(763), CA5B(11238)

Description

General description

p-Toluenesulfonamide undergoes FeCl₃-catalyzed direct substitution reaction with benzylic and allylic alcohols.It is employed as nucleophile in tetrabutylammonium fluoride (TBAF) catalyzed vinyl aziridine opening reaction.

Application

p-Toluenesulfonamide was used to prepare the precursor required for synthesis of ethyl 6-phenyl-1-tosyl-1,2,5,6-tetrahydropyridine-3-carboxylate.

Still not finding the right product?

Explore all of our products under p-Toluenesulfonamide

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

395.6 °F - closed cup

flash_point_c

202 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

PHOSPHINE-CATALYZED [4+2] ANNULATION: SYNTHESIS OF ETHYL 6-PHENYL-1-TOSYL-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLATE.

Kui Lu et al.

Organic syntheses; an annual publication of satisfactory methods for the preparation of organic chemicals, 2009(86), 212-224 (2010-02-18)

An efficient FeCl3 -catalyzed amidation reaction of secondary benzylic and allylic alcohols with carboxamides or p-toluenesulfonamide.

Jana U, et al.

Tetrahedron Letters, 42(37), 6433-6435 (2001)

Ligand binding efficiency: trends, physical basis, and implications.

Charles H Reynolds et al.

Journal of medicinal chemistry, 51(8), 2432-2438 (2008-04-03)

Ligand efficiency (i.e., potency/size) has emerged as an important metric in drug discovery. In general, smaller, more efficient ligands are believed to have improved prospects for good drug properties (e.g., bioavailability). Our analysis of thousands of ligands across a variety

View All Related Papers

Global Trade Item Number

SKU	GTIN
105902-1KG	04061825894515
105902-250G	04061838673268