Nukol Capillary GC Column

Application: The incorporation of acid functional groups into the phase lends an acidic character to this column, useful for analyses of volatile acidic compounds. Difficult to analyze carboxylic acids (free fatty acids) can be analyzed with excellent peak shape and minimal adsorption.
USP Code: This column meets USP G25 and G35 requirements.
Phase:

• Bonded
• Acid-modified poly(ethylene glycol)

Temp. Limits:

• 60 °C to 200 °C (isothermal) or 220 °C (programmed)

Capillary GC column is also known as open tubular column. The carrier gas flows through the central aperture and is unrestricted throughout the length of the column.

The Nukol column is used for the analysis ofvolatile short-chain fatty acids (SCFAs). The Nukol column is specificallydesigned for volatile acids, allowing for the effective separation andquantification of these compounds in fecal samples. The GC system with theNukol column facilitates the measurement of SCFA concentrations, which are important metabolic products of gut microbial fermentation.
Reference: David, L., Maurice, C., Carmody, R. et al. Diet rapidly and reproducibly alters the human gutmicrobiome. Nature 505,559–563 (2014)

Nukol Capillary GC Column may be used in the quantitative determination of C₂-C₈ free carboxylic acids in dairy products by gas chromatography. It may also be used for the determination of the free concentration of valproic acid in human plasma by equilibrium dialysis followed by solid-phase microextraction (SPME) and capillary gas chromatography.

We offer a variety of chromatography accessories including analytical syringes