SAB4300128
Anti-phospho-NOS3 (pSer1177) antibody produced in rabbit
affinity isolated antibody
Synonym(s):
ECNOS, NOS, NOSIII, eNOS
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About This Item
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
14
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
predicted mol wt 133 kDa
species reactivity
mouse, rat, human
concentration
1 mg/mL
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pSer1177)
Gene Information
human ... NOS3(4846)
Immunogen
Peptide sequence around phosphorylation site of serine 1177 (T-Q-S(p)-F-S), according to the protein NOS3.
Application
Recommended dilutions
Western Blot 1:500 - 1:1000
Optimal dilutions should be determined by the user.
Western Blot 1:500 - 1:1000
Optimal dilutions should be determined by the user.
Biochem/physiol Actions
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Payal Chakraborty et al.
Chemico-biological interactions, 313, 108821-108821 (2019-09-17)
Decrease in the bioavailability of vasoactive nitric oxide (NO), derived from the endothelial nitric oxide synthase (NOS3), underlines vascular endothelial damage. Our expanding knowledge on mature red blood cells (RBCs) makes it supposable that RBCs might contribute to vascular function
Contribution of eNOS variants to the genetic susceptibility of coronary artery disease in a Tunisian population.
Ben Ali M
Genetic Testing and Molecular Biomarkers, 19, 203-208 (2015)
Naoyuki Otani et al.
Hypertension research : official journal of the Japanese Society of Hypertension, 41(11), 923-931 (2018-09-07)
This study was designed to investigate the effects of uric acid on vascular endothelial function in measurements carried out either at the bedside or the laboratory bench. First, we performed reactive hyperemia peripheral arterial tonometry using an EndoPAT 2000 device
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAB4300128-100UG | 04061832702278 |