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About This Item
Empirical Formula (Hill Notation):
C19H25NO · C4H6O6
CAS Number:
Molecular Weight:
433.49
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
200-767-3
MDL number:
Quality Level
assay
≥98% (HPLC)
form
powder
optical activity
[α]22/D −35°, c = 0.38 in H2O(lit.)
color
white to beige
solubility
H2O: 5 mg/mL, clear
originator
Roche
SMILES string
O[C@H]([C@@H](O)C(O)=O)C(O)=O.[H][C@@]12CCCC[C@@]13CCN(CC=C)[C@@H]2Cc4ccc(O)cc34
InChI
1S/C19H25NO.C4H6O6/c1-2-10-20-11-9-19-8-4-3-5-16(19)18(20)12-14-6-7-15(21)13-17(14)19;5-1(3(7)8)2(6)4(9)10/h2,6-7,13,16,18,21H,1,3-5,8-12H2;1-2,5-6H,(H,7,8)(H,9,10)/t16-,18+,19+;1-,2-/m01/s1
InChI key
FWMLYVACGDQRFU-ZTMWJVNESA-N
Gene Information
human ... OPRD1(4985), OPRM1(4988)
Biochem/physiol Actions
Partial agonist (antagonist) at μ and δ opioid receptors.
Features and Benefits
This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Disclaimer
Photosensitive
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Ying-Chen Chen et al.
International journal of nanomedicine, 10, 7265-7274 (2015-12-15)
To alleviate the inherent problems of amphotericin B (AmB), such as poor water solubility and nephrotoxicity, a novel self-assembling mixed polymeric micelle delivery system based on lecithin and combined with amphiphilic polymers, Pluronic(®), Kolliphor(®), d-alpha tocopheryl polyethylene glycol succinate, and
Ling-Chun Chen et al.
International journal of nanomedicine, 11, 1557-1566 (2016-05-05)
Quercetin (Que) is known to have biological benefits including an anticancer effect, but low water solubility limits its clinical application. The aim of this study was to develop a lecithin-based mixed polymeric micelle (LMPM) delivery system to improve the solubility
Anushree Seth et al.
International journal of nanomedicine, 7, 5129-5136 (2012-10-12)
The influence of morphology and surface properties on the therapeutic efficacy of degradable polymeric microparticles has not been well understood. One of the primary reasons for this is the limited ability to fabricate microparticles with controlled morphology and surface properties.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| L121-5MG | 04061833949238 |
