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Merck

CBL1366

Anti-CD140a Antibody, clone APA5

clone APA5, Chemicon®, from rat

Synonym(s):

PDGF Receptor alpha

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
APA5, monoclonal
Application:
ELISA, FACS, IHC, WB
Citations:
5
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biological source

rat

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

APA5, monoclonal

species reactivity

mouse

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable, flow cytometry: suitable, immunohistochemistry: suitable, western blot: suitable

isotype

IgG2aκ

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... PDGFRA(5156)

Application

Detect CD140a using this Anti-CD140a Antibody, clone APA5 validated for use in ELISA, FC, WB, IH.
Flow Cytometry: ≤ 1 μg per 10E6 cells

ELISA

Immunohistochemistry: 10μg/mL

Blocking of Ligand Binding

Western Blotting

Optimal working dilutions must be determined by the end user.
Research Category
Signaling
Research Sub Category
Growth Factors & Receptors

Biochem/physiol Actions

Specifically recognizes mouse CD140a, the alpha chain of PDGF receptor. A receptor tyrosine kinase, PDGFRa forms dimers on the surface upon ligand binding and phosphorylates substrates. CD140a is expressed by embryonic tissues and mesenchymal-derived cells of the adult mouse tissues.

Physical form

Format: Purified
Purified immunoglobulin in PBS, 150 mM NaCl, pH 7.2, containing 0.09% sodium azide.

Preparation Note

Maintain at 2-8°C for up to 12 months from date of receipt.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Maria Anesti et al.
Cells, 11(11) (2022-06-11)
Two main stem cell pools exist in the postnatal mammalian brain that, although they share some "stemness" properties, also exhibit significant differences. Multipotent neural stem cells survive within specialized microenvironments, called niches, and they are vulnerable to ageing. Oligodendroglial lineage-restricted
Julien Vernerey et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(7), 3240-3250 (2013-02-15)
Ciliary neurotrophic factor (CNTF) has been shown to be expressed after brain lesions and in particular after demyelination. Here, we addressed the role of this cytokine in the regulation of neural progenitor migration in the adult rodent brain. Using an
Sarah Moyon et al.
Nature communications, 12(1), 3359-3359 (2021-06-09)
The mechanisms regulating myelin repair in the adult central nervous system (CNS) are unclear. Here, we identify DNA hydroxymethylation, catalyzed by the Ten-Eleven-Translocation (TET) enzyme TET1, as necessary for myelin repair in young adults and defective in old mice. Constitutive



Global Trade Item Number

SKUGTIN
CBL136604053252322754