Skip to Content
Merck

KITALYSIS-SM

KitAlysis High-Throughput Suzuki-Miyaura Cross-Coupling Reaction Screening Kit - Pack of 4

Synonym(s):

Suzuki-Miyaura Cross-Coupling

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

NACRES:
NA.22
UNSPSC Code:
12161600
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


product line

KitAlysis

reaction suitability

reaction type: Cross Couplings, reaction type: Suzuki-Miyaura Coupling, reagent type: catalyst
core: palladium

functional group

phosphine

Application

Screening kit for Suzuki-Miyaura cross-coupling reaction. Step-by-step user guide and a downloadable experimental excel sheets are provided in the below hyperlink.
Step-by-Step Guide for Suzuki-Miyaura Cross-Coupling Reaction Screening Kit
Downloadable experimental excel sheet

Each kit contains 4 customizable screening sets that include the following components:
  • 6 x 4 pre-weighed catalysts in glass vials loaded with stir bars and topped with cap mat.
  • 1 (2 mL) ampule each of Toluene, THF, n-Butanol, DMAc, and aq. 1.5 M K3PO4.
  • 4 NEW KitAlysis 24-Well Reaction Block Replacement Films.
  • 4 substrate reaction vials with stir bars.
  • 1 internal standard.
Monitor reaction progress via TLC-MS by following this protocol

Best when used with KitAlysis Benchtop Inertion Box and 24-well Reaction Block (sold separately).

Features and Benefits

  • Designed and tested by synthetic chemists.
  • Easily run 24-microscale reactions in parallel.
  • 10 μmol reactions with 1 μmol catalyst, 3 equiv. base, 0.1 M concentration.
  • Customizable Excel Template for quick calculations and easy incorporation into electronic laboratory notebooks.

Legal Information

KitAlysis is a trademark of Sigma-Aldrich Co. LLC


Kit Components Only

Product No.
Description

  • SnapIT Ampule Opener, Regular, for 1-2ml, 5-10ml, 10-15ml ampoules 1 EA

Kit Components Also Available Separately

Product No.
Description
SDS & Pricing

  • Pd-PEPPSI-IPent catalyst, ≥95% 5 µmol
    SDS

  • SPhos Pd G2 5 µmol
    SDS

  • cataCXium® A Pd G2 5 µmol
    SDS

  • XPhos Pd G3, 98%, 1:1 MTBE adduct 5 µmol
    SDS

  • P(Cy3) Pd G3, 97% 5 µmol
    SDS

  • APhos Pd G3, 97% 5 µmol
    SDS

  • Toluene, anhydrous, ZerO2®, 99.8% 8 mL
    SDS

See All (12)

signalword

Danger

target_organs

Central nervous system, Respiratory system

supp_hazards

Storage Class

3 - Flammable liquids

flash_point_f

1.4 °F

flash_point_c

-17 °C

wgk

WGK 3

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 2 Inhalation - STOT SE 3



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library


Protocols

A step-by-step protocol guide for KitAlysis Suzuki-Miyaura Cross-Coupling Reaction Screening Kit.

Articles

KitAlysis High-Throughput Screening Kits provide solution to efficiently identify or optimize suitable catalytic reaction conditions. Chemist can rapidly run 24 unique micro scale reactions in parallel with tailored conditions.

Materials Included in your KITALYSIS-24PD-2PK High-Throughput Screening Kit

Multiple tools have been created to ensure your success with kit set up. Start with the more detailed guide to ensure you are comfortable with all of the steps before using the quick guides on the excel worksheet. Remember that while the technique is new, it is still organic chemistry and so the steps will seem easy once you try just one kit. It is just a new way of approaching something you are already very good at.

View All Articles

Related Content

有机合成中的化学反应设计和优化旨在精确改变反应参数,以达到最佳效果,找到通向目标分子的途径。

Chemical reaction design and optimization in organic synthesis aims to precisely alter reaction parameters to achieve optimum results in finding pathways to target molecules.


High-Throughput Experimentation in Catalysis and Materials Science.
Gordillo A, et al.
Ullmann's Encyclopedia of Industrial Chemistry (2014)
Scientist-Led High-Throughput Experimentation (HTE) and Its Utility in Academia and Industry.
Schmink JR, et al.
Aldrichimica Acta, 46, 71-80 (2013)
Spencer D Dreher et al.
Journal of the American Chemical Society, 130(29), 9257-9259 (2008-06-28)
Microscale parallel experimentation was used to discover three catalyst systems capable of coupling secondary organotrifluoroborates with sterically and electronically demanding aryl chlorides and bromides. The ensuing results represent the first comprehensive study of alkylboron coupling to aryl chlorides and, in



Global Trade Item Number

SKUGTIN
KITALYSIS-SM-4PAK04061833553756