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Merck

P5177

Sigma-Aldrich

Methyl palmitate

≥99% (capillary GC)

Synonym(s):

n-Hexadecanoic acid methyl ester, Methyl hexadecanoate, Palmitic acid methyl ester

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About This Item

Linear Formula:
CH3(CH2)14CO2CH3
CAS Number:
112-39-0
Molecular Weight:
270.45
Beilstein:
1780973
EC Number:
203-966-3
MDL number:
MFCD00008994
UNSPSC Code:
12352211
PubChem Substance ID:
24898607
NACRES:
NA.25

Key Documents

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biological source

plant (palm)

Quality Level

100

Assay

≥99% (capillary GC)

form

solid

refractive index

n20/D 1.4512 (lit.)

bp

185 °C/10 mmHg (lit.)

mp

32-35 °C (lit.)

density

0.852 g/mL at 25 °C (lit.)

functional group

ester

lipid type

saturated FAs

shipped in

ambient

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCCCCCC(=O)OC

InChI

1S/C17H34O2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17(18)19-2/h3-16H2,1-2H3

InChI key

FLIACVVOZYBSBS-UHFFFAOYSA-N

Gene Information

human ... CNR1(1268), CNR2(1269)
rat ... Faah(29347)

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General description

Methyl palmitate (PAME), a fatty acid ester of palmitic acid, is a muscurinic receptors antagonist. Methyl palmitate functions as a vasodilator and relaxes the arterioles in retina upon electrical depolarization. In the superior cervical ganglion, methyl palmitate modulates nicotinic receptor. Endogenous methyl palmitate modulates nicotinic receptor-mediated transmission in the superior cervical ganglion. PAME activates Kv7 channels and promotes perivascular adipose tissue.

Application

Methyl palmitate has been used to test impact of cerebral blood flow using laser doppler flowmetry (LDF) experiments and as a standard to determine retention indices (RIs) using gas chromatograph−mass spectrometer

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113.0 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCP4988
MKCN9967
MKCM4819
MKCM0360
MKCJ7076

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Palmitic acid methyl ester is a novel neuroprotective agent against cardiac arrest
Lee RHC, et al.
Prostaglandins, Leukotrienes, and Essential Fatty Acids (2018)
Palmitic acid methyl ester and its relation to control of tone of human visceral arteries and rat aortas by perivascular adipose tissue
Wang N, et al.
Frontiers in Physiology, 9 (2018)
Jiao Liu et al.
Biotechnology for biofuels, 8, 229-229 (2016-01-01)
Fatty acid composition is an important physiological parameter of microalgae, which is taken as the third generation alternative resource of biodiesel. To boost microalgal research and applications, a convenient, rapid, and acid-catalyzed transesterification procedure that satisfies the demand for the
Endogenous methyl palmitate modulates nicotinic receptor-mediated transmission in the superior cervical ganglion
Lin HW, et al.
Proceedings of the National Academy of Sciences of the USA, 1051(49), 19526-19531 (2008)
Terminal double bonds in the alkenes and acetates of defensive secretion from the thrips Suocerathrips linguis Mound & Marullo, 1994 (Thysanoptera: Phlaeothripidae)
Gehlsen U, et al.
Chemoecology, 19(2), 97-102 (2009)
View All Related Papers

Protocols

HPLC Analysis of Fatty Acid Methyl Esters (FAMES) on SUPELCOSIL LC-18

Separation of Methyl decanoate; Methyl dodecanoate; Methyl myristate; Methyl palmitate; Methyl caprylate; Methyl oleate; Methyl linoleate; Methyl linolenate; Methyl stearate

GC Analysis of Bacterial Acid Methyl Esters (BAMEs) on Equity®-1

Protocol for GC Analysis of Bacterial Acid Methyl Esters (BAMEs) on Equity®-1

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