Skip to Content
Merck

P259

Sigma-Aldrich

1-O-Palmityl-sn-glycero-3-phosphocholine

powder

Synonym(s):

1-Hexadecyl-sn-glycero-3-phosphocholine, 3-sn-Lysophosphatidylcholine, 1-hexadecyl, Lyso-PAF-C16, Lyso-platelet activating factor

Sign Into View Organizational & Contract Pricing

Select a Size

About This Item

Empirical Formula (Hill Notation):
C24H52NO6P
CAS Number:
52691-62-0
Molecular Weight:
481.65
MDL number:
MFCD00042932
UNSPSC Code:
12352200
PubChem Substance ID:
329820142

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

form

powder

Quality Level

100

color

white

solubility

H2O: 20 mg/mL

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COCCCCCCCCCCCCCCCC

InChI

1S/C24H52NO6P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-29-22-24(26)23-31-32(27,28)30-21-19-25(2,3)4/h24,26H,5-23H2,1-4H3/t24-/m1/s1

InChI key

VLBPIWYTPAXCFJ-XMMPIXPASA-N

Looking for similar products? Visit Product Comparison Guide

Application

1-O-Palmityl-sn-glycero-3-phosphocholine also known as Lyso-PAF-(C16) can be used as a standard in the assay of platelet-activating factor.

Biochem/physiol Actions

Accumulation of lyso-PAF in atherogenic aortas may lead to unregulated PAF formation and can cause atherosclerosis.

Preparation Note

20mg of 1-O-Palmityl-sn-glycero-3-phosphocholine dissolves in 1 ml of water.

Other Notes

Inactive form of PAF[C16]

Disclaimer

Hygroscopic

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

J X Kang et al.
The Biochemical journal, 303 ( Pt 3), 795-802 (1994-11-01)
Radioligand-binding studies were performed in primary cultured human airway epithelial cells with [3H]PAF to determine whether these cells express platelet-activating factor (PAF) receptors. Scatchard analysis of PAF binding data revealed a single class of PAF binding sites with Kd 1.8
J K Mickelson et al.
Journal of molecular and cellular cardiology, 20(6), 547-561 (1988-06-01)
Myocardial injury was produced in separated groups of anesthetized rabbits by occlusion of the left circumflex coronary artery for 1 h followed by reperfusion for 2, 4, or 6 h after release of the occlusive ligature. The ischemically-injured and reperfused
G Montrucchio et al.
The American journal of pathology, 153(5), 1589-1596 (1998-11-12)
This study investigated the presence of platelet-activating factor (PAF) in the lipid extracts of 18 primary breast carcinomas and 20 control breast tissues. The amount of PAF detected in breast carcinomas was significantly higher than in controls. The mass spectrometric
C G Qian et al.
Journal of lipid mediators, 1(2), 113-123 (1989-03-01)
Suspensions of neonatal rat myocytes were used to investigate the metabolism of [3H]PAF (1-alkyl-2-acetyl-(sn-glycero-3-phosphocholine) (GPC] and [3H]alkyllyso-GPC. [3H]Alkylacyl-GPC consisting of molecular species with four or more double bonds (87%) was the major metabolite formed when either [3H]PAF (4 x 10(-6)
R A Erger et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 45(6), 265-267 (1996-06-01)
Multiple molecular species of the eosinophil chemoattractant platelet activating factor (PAF) are produced as a result of inflammatory processes. We therefore compared the ability of three naturally occurring PAF species (C16:0, C18:0, and C18:1), which only varied at carbon 1

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service