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X600

Xanthone

Name: Xanthone
Brand: ALDRICH

97%

Synonym(s):

9-Xanthenone

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About This Item

Empirical Formula (Hill Notation):

C₁₃H₈O₂

CAS Number:

90-47-1

Molecular Weight:

196.20

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24902151

EC Number:

201-997-7

Beilstein/REAXYS Number:

140443

MDL number:

MFCD00005060

Assay:

97%

Form:

powder

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Properties

Quality Level

100

assay

97%

form

powder

bp

349-350 °C/730 mmHg (lit.)

mp

172-174 °C (lit.)

SMILES string

O=C1c2ccccc2Oc3ccccc13

InChI

1S/C13H8O2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1-8H

InChI key

JNELGWHKGNBSMD-UHFFFAOYSA-N

Gene Information

mouse ... Prkch(18755)

Description

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Synthesis and cancer cell cytotoxicity of substituted xanthenes.

Rajan Giri et al.

Bioorganic & medicinal chemistry, 18(4), 1456-1463 (2010-02-05)

A series of substituted xanthenes was synthesized and screened for activity using DU-145, MCF-7, and HeLa cancer cell growth inhibition assays. The most potent compound, 9 g ([N,N-diethyl]-9-hydroxy-9-(3-methoxyphenyl)-9H-xanthene-3-carboxamide), was found to inhibit cancer cell growth with IC(50) values ranging from

Xanthone derivatives as potential inhibitors of miRNA processing by human Dicer: targeting secondary structures of pre-miRNA by small molecules.

Asako Murata et al.

Bioorganic & medicinal chemistry letters, 23(1), 252-255 (2012-11-21)

In recent years, various biological processes have been found to be regulated by miRNA-mediated gene silencing. A small molecule that modulate the miRNA pathway will provide the biological tool for elucidating mechanisms of miRNA-mediated gene regulation, and can be the

Solid phase combinatorial synthesis of a xanthone library using click chemistry and its application to an embryonic stem cell probe.

Krishna Kanta Ghosh et al.

Chemical communications (Cambridge, England), 47(26), 7488-7490 (2011-06-02)

We report the first solid phase synthesis of a xanthone library CX and its application to embryonic stem cell probe development. The CX library was further derivatised with an activated ester resin to provide an acetylated CX (CXAC) library. Screening

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Global Trade Item Number

SKU	GTIN
X600-25G	04061837549809