A5707
Argininosuccinic acid disodium salt hydrate
≥80%
Synonym(s):
Sodium N-[[[(4S)-4-amino-4-carboxybutyl]amino]iminomethyl]-L-aspartate (2:1)
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About This Item
Empirical Formula (Hill Notation):
C10H16N4Na2O6 · xH2O
CAS Number:
Molecular Weight:
334.24 (anhydrous basis)
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Quality Level
Assay
≥80%
form
powder
storage temp.
−20°C
SMILES string
O.[Na+].[Na+].N[C@@H](CCCNC(=N)N[C@@H](CC([O-])=O)C(O)=O)C([O-])=O
InChI
1S/C10H18N4O6.2Na.H2O/c11-5(8(17)18)2-1-3-13-10(12)14-6(9(19)20)4-7(15)16;;;/h5-6H,1-4,11H2,(H,15,16)(H,17,18)(H,19,20)(H3,12,13,14);;;1H2/q;2*+1;/p-2/t5-,6-;;;/m0.../s1
InChI key
UCTAVRCIKYVVFI-VDBFCSKJSA-L
Related Categories
Application
Argininosuccinic acid disodium salt hydrate has been used in the spectrophotometric measurement of argininosuccinate lyase (ASL) enzymatic activity in cell extracts.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Liyan Hu et al.
The Journal of biological chemistry, 288(48), 34599-34611 (2013-10-19)
Argininosuccinic aciduria (ASA) is an autosomal recessive urea cycle disorder caused by deficiency of argininosuccinate lyase (ASL) with a wide clinical spectrum from asymptomatic to severe hyperammonemic neonatal onset life-threatening courses. We investigated the role of ASL transcript variants in
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