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Merck

664049

Sigma-Aldrich

PAMAM Dendrimer Kit, generations 4-7

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About This Item

UNSPSC Code:
12162002
eCl@ss:
32161000
NACRES:
NA.23

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description

amino surface groups

feature

core type ethylenediamine core (2-carbon core)

storage temp.

2-8°C

Related Categories

General description

Ethylenediamine-core poly(amidoamine) (PAMAM) dendrimers are highly branched, “tree-like” core-shell nanostructures made up of amide and amine functional subunits.

Application

PAMAM Dendrimer Kit, generations 4-7 can be used to formulate poorly water-soluble drugs to increase water solubility, and therefore enhance the bioavailability of these drugs. It can also be applied to catalysts and organic molecules, where dendrimers function as solubility enhancers and modifiers, allowing to mix otherwise immiscible materials.

Packaging

unit weight includes solvent

Legal Information

Manufactured by Dendritech®, Inc.
Dendritech is a registered trademark of Dendritech, Inc.

Kit Components Also Available Separately

Product No.
Description
SDS
  • 412449PAMAM dendrimer, ethylenediamine core, generation 4.0 solution, 10 wt. % in methanol 1 gSDS
  • 536709PAMAM dendrimer, ethylenediamine core, generation 5.0 solution, 5 wt. % in methanol 1 gSDS
  • 536717PAMAM dendrimer, ethylenediamine core, generation 6.0 solution, 5 wt. % in methanol 1 gSDS
  • 536725PAMAM dendrimer, ethylenediamine core, generation 7.0 solution, 5 wt. % in methanol 1 gSDS

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Storage Class Code

3 - Flammable liquids

Flash Point(F)

51.8 °F - closed cup

Flash Point(C)

11 °C - closed cup

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Esen Efeoglu et al.
The Analyst, 142(20), 3848-3856 (2017-09-13)
Although consumer exposure to nanomaterials is ever increasing, with potential increased applications in areas such as drug and/or gene delivery, contrast agents and diagnosis, the determination of the cyto- and geno-toxic effects of nanomaterials on human health and the environment
Heck reactions catalyzed by PAMAM-dendrimer encapsulated Pd (0) nanoparticles
Rahim EH, et al.
Nano Letters, 1(9), 499-501 (2001)

Articles

Magnetic Nanoparticles for Cancer Theranostics

The recent emergence of a number of highly functional nanomaterials has enabled new approaches to the understanding, diagnosis, and treatment of cancer.

Solubility Enhancement with Dendrimers

Replace volatile organic solvents with water due to environmental concerns, overcoming challenges in solubility.

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Advanced Applications of Engineered Nanomaterials

This thematic issue focuses on the emerging applications of nanomaterials. Nanomaterials are defined as substances with at least one dimension smaller than 100 nm.

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