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545864

(S)-(−)-Aminoglutethimide

Name: (<I>S</I>)-(−)-Aminoglutethimide
Brand: ALDRICH

97%

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About This Item

Empirical Formula (Hill Notation):

C₁₃H₁₆N₂O₂

CAS Number:

57288-03-6

Molecular Weight:

232.28

MDL number:

MFCD18974129

UNSPSC Code:

12352005

PubChem Substance ID:

24878856

NACRES:

NA.22

Assay:

97%

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Properties

Quality Level

100

assay

97%

optical activity

[α]20/D −160°, c = 1 in methanol

mp

115.5-119.5 °C (lit.)

SMILES string

CC[C@]1(CCC(=O)NC1=O)c2ccc(N)cc2

InChI

1S/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-6H,2,7-8,14H2,1H3,(H,15,16,17)/t13-/m0/s1

InChI key

ROBVIMPUHSLWNV-ZDUSSCGKSA-N

Gene Information

human ... CYP17A1(1586), CYP19A1(1588)

Description

Application

(S)-(−)-Aminoglutethimide can be used:

As an internal standard in the separation of the pyridoglutethimide enantiomers using the HPLC technique.
In the study of steroid hormones role on human cytomegalovirus replication in adrenocortical cells.

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number

15330PI

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Human cytomegalovirus productively infects adrenocortical cells and induces an early cortisol response.

Marta Trevisan et al.

Journal of cellular physiology, 221(3), 629-641 (2009-08-19)

Following our recent findings on the presence of human cytomegalovirus (HCMV) in the normal human adrenal cortex and in adrenocortical tumors, especially in cortisol-secreting tumors, aim of the present study was to investigate the direct effects of HCMV infection on

Global Trade Item Number

SKU	GTIN
545864-500MG	04061832896199