1547007
USP
Polymyxin B sulfate
United States Pharmacopeia (USP) Reference Standard
Grade
pharmaceutical primary standard
API family
polymyxin
양식
powder
제조업체/상표
USP
응용 분야
USP Biologics
pharmaceutical (small molecule)
형식
neat
저장 온도
2-8°C
SMILES string
[S](=O)(=O)(O)O.N1CCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C1=O)CCO)CCN)CCN)CC(C)C)Cc2ccccc2)CCN)NC(=O)C(NC(=O)C(NC(=O)C(NC=O)CCN)CCO)CCN
InChI
1S/C48H82N16O13.H2O4S/c1-27(2)24-37-47(76)59-32(11-19-52)41(70)56-31(10-18-51)43(72)61-35(14-22-65)39(68)54-21-13-34(45(74)57-33(12-20-53)44(73)64-38(48(77)63-37)25-28-6-4-3-5-7-28)60-42(71)30(9-17-50)58-46(75)36(15-23-66)62-40(69)29(8-16-49)55-26-67;1-5(2,3)4/h3-7,26-27,29-38,65-66H,8-25,49-53H2,1-2H3,(H,54,68)(H,55,67)(H,56,70)(H,57,74)(H,58,75)(H,59,76)(H,60,71)(H,61,72)(H,62,69)(H,63,77)(H,64,73);(H2,1,2,3,4)
InChI key
HNDFYNOVSOOGDU-UHFFFAOYSA-N
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일반 설명
Polymyxin B sulfate is a mixture of closely related cyclic polypeptides produced by Bacillus polymyxa. It disrupts the integrity of Gram-negative bacterial membranes by binding to lipopolysaccharides. The USP reference standard is used in microbiological potency assays and system suitability testing.
The USP biologics antibiotics category includes a wide range of antimicrobial agents that are essential in treating bacterial infections. These antibiotics are derived from various natural sources or synthesized to combat specific pathogens effectively. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of antibiotic therapeutics throughout their lifecycle.
The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.
애플리케이션
- Bacitracin and Polymyxin B Sulfate Topical Aerosol®
- Oxytetracycline Hydrochloride and Polymyxin B Sulfate Ointment
- Polymyxin B Sulfate and Trimethoprim Ophthalmic Solution
- Bacitracin Zinc and Polymyxin B Sulfate Ointment
- Polymyxin B Sulfate and Hydrocortisone Otic Solution
- Chloramphenicol and Polymyxin B Sulfate Ophthalmic Ointment
- Oxytetracycline Hydrochloride and Polymyxin B Sulfate Ophthalmic Ointment
분석 메모
기타 정보
법적 정보
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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