SML1042
Eptifibatide acetate
≥98% (HPLC), GPIIb/IIIa antagonist, powder
동의어(들):
Cyclo(S,S)-Mpr(Har)GDWPC-NH2 acetate, N6-(Aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide cyclic (16)-disulfide acetate
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C35H49N11O9S2 · xC2H4O2
CAS 번호:
Molecular Weight:
831.96 (free base basis)
UNSPSC 코드:
51111800
NACRES:
NA.77
제품 이름
Eptifibatide acetate, ≥98% (HPLC)
Quality Level
분석
≥98% (HPLC)
양식
powder
저장 조건
desiccated
색상
white to beige
solubility
H2O: 2 mg/mL, clear (warmed)
배송 상태
wet ice
저장 온도
−20°C
일반 설명
Eptifibatide acetate is a cyclic heptapeptide. It is the member of the class arginin-glycin-aspartat-mimetics. Eptifibatide has a short half-life. The drug decreases the risk of myocardial infarction (MI). Eptifibatide acetate might be associated with thrombocytopenia.
생화학적/생리학적 작용
Eptifibatide is a specific inhibitor of fibrinogen binding to the platelet membrane integrin glycoprotein GPIIb/IIIa receptor, preventing platelet aggregation. Eptifibatide binds reversibly and competitively.
Eptifibatide is a specific inhibitor of fibrinogen binding to the platelet membrane integrin glycoprotein GPIIb/IIIa receptor.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Recurrent acute thrombocytopenia in the hospitalized patient: Sepsis, DIC, HIT, or antibiotic-induced thrombocytopenia
Rousan TA, et al.
American Journal of Hematology, 85(1), 71-74 (2010)
Current role of platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes
Bhatt DL and Topol EJ
JAMA : The Journal of the American Medical Association, 284(12), 1549-1558 (2000)
Eptifibatide: A cyclic peptide that selectively inhibits platelet glycoprotein IIb/IIIa
Heras M and Escolar G
Drugs Today (Barc), 36, 295-311 (2000)
Clinical review: traumatic brain injury in patients receiving antiplatelet medication
Beynon C, et al.
Critical Care, 16(4), 228-228 (2012)
Jaqueline Gomes Rosa et al.
Toxicon : official journal of the International Society on Toxinology, 159, 50-60 (2019-01-25)
Victims of Bothrops jararaca snakebites manifest bleedings, blood incoagulability, platelet dysfunction, and thrombocytopenia, and the latter has been directly implicated in the genesis of hemorrhagic diathesis. We addressed herein the direct effects of B. jararaca venom (BjV) on ex vivo
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