SAB4702062
Monoclonal Anti-HLA-E purified produced in mouse
동의어(들):
HLA class I histocompatibility antigen, MHC class I antigen E, alpha chain E
결합
unconjugated
Quality Level
항체 생산 유형
primary antibodies
클론
MEM-E/02, monoclonal
양식
buffered aqueous solution
종 반응성
( Non-human primates), human
농도
1 mg/ml
기술
immunohistochemistry: suitable
western blot: suitable
동형
IgG1
UniProt 수납 번호
저장 온도
2-8°C
타겟 번역 후 변형
unmodified, unmodified
유전자 정보
human ... HLA-E(3133)
일반 설명
HLA-E (human leukocyte antigen E) is a non-classical MHC I antigen, which is important for dialogue with NK cells and their regulation through interaction with CD94/NKG2 receptor. Like other MHC I molecules, transmembrane HLA-E molecule (45 kDa) associates with beta2 microglobulin. Unlike HLA-G, expression of HLA-E molecules is not so restricted, but it has been detected at least at mRNA level in virtually all cells and tissues examined. In peripheral blood, HLA-E protein is expressed at least in all mononuclear cells, but in different quantity (B cells and monocytes more than T cells and NK cells).
면역원
Recombinant human HLA-E denaturated heavy chain.
생화학적/생리학적 작용
The antibody MEM-E/02 specifically reacts with an extracellular epitope on denaturated heavy chain of human HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of all human cell types.
물리적 형태
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
제조 메모
Purified by protein-A affinity chromatography.
Store at 2-8°C. Do not freeze.
기타 정보
The antibody solution should be gently mixed before use.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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