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Merck

S6942

Sigma-Aldrich

Staurosporine solution from Streptomyces sp.

Ready Made Solution, 1 mM in DMSO (100 μg/214 μL)

동의어(들):

Antibiotic AM-2282

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

EC Number:
200-664-3
MDL number:
MFCD04041131
UNSPSC 코드:
12352200
NACRES:
NA.77

주요 문서

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기술 서비스
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제품 이름

Staurosporine solution from Streptomyces sp., Ready Made Solution, 1 mM in DMSO (100 μg/214 μL)

Quality Level

300

분석

>98% (HPLC)

농도

1 mM in DMSO (100 μg/214 μL)

기술

cell culture | mammalian: suitable

항생제 활성 스펙트럼

fungi

동작 모드

enzyme | inhibits

배송 상태

wet ice

저장 온도

−20°C

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관련 카테고리

일반 설명

Chemical structure: indol derivative

애플리케이션

Staurosporine solution from Streptomyces sp. was used to study the effect of PKC inhibition on signaling mediated by angiotensin II.3 It was used to induce cell death in Jurkat cells.4

생화학적/생리학적 작용

Potent cell-permeable inhibitor of protein kinase C. Induces apoptosis in Jurkat cells.
Potent inhibitor of phospholipid/calcium-dependent protein kinase. Inhibits the upregulation of VEGF expression in tumor cells.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

188.6 °F - closed cup

Flash Point (°C)

87 °C - closed cup

개인 보호 장비

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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시험 성적서(COA)

Lot/Batch Number
059M4176V
11181138
038M4036V
11171011
047M4040V

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent of Coronavirus Disease 2019 (COVID-19). There is a dire need for novel effective antivirals to treat COVID-19, as the only approved direct-acting antiviral to date is remdesivir, targeting the
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G Warnes et al.
Cytometry. Part A : the journal of the International Society for Analytical Cytology, 79(3), 181-191 (2011-01-22)
The standard method of distinguishing apoptotic and oncotic cells has been by microscopic analysis of nuclei and cell membrane morphology. Thus a rapid test for analyzing large numbers of cells in the study of cell necrobiology has not been possible
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Chemotherapy-induced peripheral neuropathy (CIPN), a consequence of peripheral nerve fiber dysfunction or degeneration, continues to be a dose-limiting and debilitating side effect during and/or after cancer chemotherapy. Paclitaxel, a taxane commonly used to treat breast, lung, and ovarian cancers, causes
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