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Merck

N1638

Sigma-Aldrich

Nystatin Suspension

suspension, non-animal origin, suitable for cell culture, BioReagent

동의어(들):

Fungicidin, Mycostatin

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제품정보 (DICE 배송 시 비용 별도)

CAS 번호:
UNSPSC 코드:
12352207
PubChem Substance ID:
NACRES:
NA.76
기술 서비스
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제품 이름

Nystatin Suspension, suspension, 10,000 unit/mL in DPBS, BioReagent, suitable for cell culture

제품 라인

BioReagent

Quality Level

양식

suspension

농도

10,000 unit/mL in DPBS

기술

cell culture | mammalian: suitable

불순물

endotoxin, tested

색상

yellow

항생제 활성 스펙트럼

fungi
yeast

동작 모드

cell membrane | interferes

배송 상태

dry ice

저장 온도

−20°C

SMILES string

C[C@@H]1OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@]2(O)C[C@H](O)[C@H]([C@H](C[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)\C=C\C=C\C=C\C=C\CC\C=C\C=C\[C@H](C)[C@@H](O)[C@@H]1C)O2)C(O)=O

InChI

1S/C47H75NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-36(53)35(52)20-19-31(49)21-32(50)22-33(51)23-39(55)62-29(3)28(2)42(27)56/h5-6,8,10-18,27-38,40-44,46,49-54,56-58,61H,7,9,19-26,48H2,1-4H3,(H,59,60)/b6-5+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28+,29-,30+,31+,32+,33+,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1

InChI key

VQOXZBDYSJBXMA-QEKUPDCNSA-N

일반 설명

Chemical structure: polyene

애플리케이션

Nystatin suspension has been used:
  • to inhibit caveolin-mediated endocytosis
  • as a component of Eagle′s minimum essential medium (EMEM)
  • to enumerate lactic acid bacteria (LAB)
  • in preventing cell culture contamination and inducing interleukin (IL)-1, IL-8, and tumor necrosis factor a secretion in toll-like receptor 2 (TLR2)-expressing THP1 cells.
This product is recommended for use in cell culture applications at 24 mL/L.

생화학적/생리학적 작용

Nystatin is a polyene, broad-spectrum antibiotic, which modifies the microstructure of lipid rafts. It can sequester cholesterol present on the cell membrane of eukaryotes. Nystatin regulates immune responses through cytokine signaling, lymphocyte activation and pathogen recognition.

제조 메모

It is 0.1μ filtered and cell culture tested.

기타 정보

Nystatin suspension available in 20 mL and 100 mL pack size.
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

면책조항

This product is stable at 37°C for three days.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

A method to maintain mammalian cells for days alive at 4 C
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Conservation characteristics of corn ears and stover ensiled with the addition of Lactobacillus plantarum MTD-1, Lactobacillus plantarum 30114, or Lactobacillus buchneri 11A44
Lynch JP, et al.
Journal of Dairy Science, 95(4), 2070-2080 (2012)
Liu He et al.
eLife, 9 (2020-04-16)
The development of a polarized neuron relies on the selective transport of proteins to axons and dendrites. Although it is well known that the microtubule cytoskeleton has a central role in establishing neuronal polarity, how its specific organization is established
Nystatin enhances the immune response against Candida albicans and protects the ultrastructure of the vaginal epithelium in a rat model of vulvovaginal candidiasis
Zhang X, et al.
BMC Microbiology, 18(1), 166-166 (2018)
Quantification of gold nanoparticle cell uptake under controlled biological conditions and adequate resolution
Rothen-Rutishauser B, et al.
Nanomedicine (London, England), 9(5), 607-621 (2014)

문서

Prevent fungal, yeast, and mold contamination in cell cultures. Discover the best antifungal agent for your cultures with the extensive Sigma® antifungal collection.

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