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Merck

M8750

Sigma-Aldrich

(+)-Methamphetamine hydrochloride

동의어(들):

d-Desoxyephedrine hydrochloride, d-N,α-Dimethylphenethylamine hydrochloride, Methylamphetamine hydrochloride

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C10H15N · HCl
CAS 번호:
51-57-0
Molecular Weight:
185.69
EC Number:
200-106-9
MDL number:
MFCD00056130
UNSPSC 코드:
12352116
PubChem Substance ID:
24897282
NACRES:
NA.77

주요 문서

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기술 서비스
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기술 서비스
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도움 문의

Quality Level

200

약물 제어

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal); Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet

drug control

kontrollierte Droge in Deutschland

기술

HPLC: suitable
gas chromatography (GC): suitable

solubility

H2O: soluble
ethanol: soluble

응용 분야

forensics and toxicology
pharmaceutical (small molecule)
veterinary

주관자

Teva

SMILES string

Cl[H].CN[C@@H](C)Cc1ccccc1

InChI

1S/C10H15N.ClH/c1-9(11-2)8-10-6-4-3-5-7-10;/h3-7,9,11H,8H2,1-2H3;1H/t9-;/m0./s1

InChI key

TWXDDNPPQUTEOV-FVGYRXGTSA-N

유전자 정보

human ... SLC6A2(6530), SLC6A3(6531), SLC6A4(6532)

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관련 카테고리

생화학적/생리학적 작용

Sympathomimetic with more potent central effects than amphetamine. It is transported into terminals via the monoamine transporters and induces release of dopamine, norepinephrine, epinephrine, and serotonin. Dopamine release is important for the addictive properties of methamphetamine while norepinephrine and epinephrine release are important for the cardiovascular effects. Serotonin neurotoxin.

특징 및 장점

This compound was developed by Teva. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

기타 정보

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

법적 정보

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

픽토그램

Skull and crossbones
GHS06

신호어

Danger

유해 및 위험 성명서

H300,H336

예방조치 성명서

P301 + P310 + P330

Hazard Classifications

Acute Tox. 2 Oral - STOT SE 3

표적 기관

Central nervous system

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
SLCL6640
SLCC8107
SLBS1221V
SLBT1207
SLBV9808

적합한 버전을 찾을 수 없으신가요?

특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

G J Rivière et al.
The Journal of pharmacology and experimental therapeutics, 291(3), 1220-1226 (1999-11-24)
The purpose of these studies was to better understand the behavioral effects and pharmacokinetics of an i.v. bolus dose of (+)-methamphetamine [(+)-METH] in a rat model of (+)-METH abuse. We characterized the behavioral effects after increasing (+)-METH doses (0.1, 0.3
Kaveh Shahveisi et al.
Pharmacology, biochemistry, and behavior, 185, 172759-172759 (2019-08-16)
Susceptibility to interference can be a result of memory retrieval and reconsolidation. Given the fact that addiction develops through the neural mechanisms of learning and memory, it would not be surprising that a consolidated drug reward memory may also be
Noémie Cresto et al.
International journal of molecular sciences, 22(13) (2021-07-03)
Alpha-synuclein (α-syn) and leucine-rich repeat kinase 2 (LRRK2) play crucial roles in Parkinson's disease (PD). They may functionally interact to induce the degeneration of dopaminergic (DA) neurons via mechanisms that are not yet fully understood. We previously showed that the
Shaolin Yang et al.
Addiction biology, 20(1), 69-79 (2013-08-06)
(1) H magnetic resonance spectroscopy has demonstrated alterations in several neurometabolites in methamphetamine (METH)-dependent individuals in brain regions implicated in addiction. Yet, it is unclear whether these neurochemicals return to homeostatic levels after an individual abstains from drug use, a
Betina González et al.
Neuropharmacology, 87, 188-197 (2014-02-18)
Chronic use of methamphetamine (METH) leads to long-lasting cognitive dysfunction in humans and in animal models. Modafinil is a wake-promoting compound approved for the treatment of sleeping disorders. It is also prescribed off label to treat METH dependence. In the
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