M1000
L-(−)-Malic acid
≥95% (titration)
동의어(들):
(S)-(−)-2-Hydroxysuccinic acid, L-Hydroxybutanedioic acid
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
HO2CCH2CH(OH)CO2H
CAS 번호:
Molecular Weight:
134.09
Beilstein:
1723541
EC Number:
MDL number:
UNSPSC 코드:
12352106
PubChem Substance ID:
NACRES:
NA.22
Quality Level
분석
≥95% (titration)
양식
powder
pKa(25 °C)
(1) 3.46, (2) 5.10
mp
101-103 °C ((lit.))
101-103 °C (lit.)
solubility
water: 100 mg/mL, clear to very slightly hazy, colorless
density
1,595 g/cm3 at 68 °F
SMILES string
O[C@@H](CC(O)=O)C(O)=O
O[C@@H](CC(O)=O)C(O)=O
InChI
1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/t2-/m0/s1
1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/t2-/m0/s1
InChI key
BJEPYKJPYRNKOW-REOHCLBHSA-N
BJEPYKJPYRNKOW-REOHCLBHSA-N
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일반 설명
L-Malic acid is the naturally occurring isomer of malic acid, found mainly in sour and unripe fruits.
애플리케이션
L-(-)-Malic acid may be used to prepare:
- diethyl (S)-malate
- ethyl (R)-2-hydroxyl-4-phenylbutanoate
- ethyl (S)-2-hydroxyl-4-phenylbutanoate
- D-homophenylalanine ethyl ester hydrochloride
- furo[3,2-i]indolizines
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
A stereospecific synthesis of (-)-Bestatin from L-malic acid.
Norman BH and Morris ML.
Tetrahedron Letters, 33(45), 6803-6806 (1992)
Asymmetric synthesis of furo [3, 2-i] indolizines from L-malic acid.
Lee YS, et al.
Tetrahedron, 55(15), 4631-4636 (1999)
A practical synthesis of ethyl (R)-and (S)-2-hydroxy-4-phenylbutanoate and D-homophenylalanine ethyl ester hydrochloride from L-malic acid.
Lin WQ, et al.
Tetrahedron Asymmetry, 12(11), 1583-1587 (2001)
Mc Murry JE
Organic Chemistry , Biological Approach (2016)
Elena Grossini et al.
PloS one, 10(4), e0124742-e0124742 (2015-04-17)
Levosimendan protects rat liver against peroxidative injuries through mechanisms related to nitric oxide (NO) production and mitochondrial ATP-dependent K (mitoKATP) channels opening. However, whether levosimendan could modulate the cross-talk between apoptosis and autophagy in the liver is still a matter
프로토콜
Enzymatic Assay of Fumarase
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