L0636
Lectin from Triticum vulgaris (wheat)
suitable for cell culture, BioReagent, lyophilized powder
동의어(들):
WGA, Wheat germ agglutinin
무균
aseptically processed
Quality Level
제품 라인
BioReagent
양식
lyophilized powder
기술
cell culture | mammalian: suitable
불순물
salt, essentially free
저장 온도
2-8°C
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일반 설명
Lectin from Triticum vulgaris (wheat) is a dimeric glycoprotein of 36 kDa. It belongs to the family of chitin-binding proteins. Glycosylated precursor of lectin is synthesized in endoplasmic reticulum.
애플리케이션
Lectin from Triticum vulgaris (wheat) has been used:
- to conjugate with N-hydroxysuccinimide (NHS) dye
- to inhibit nuclear import
- to inhibit the nuclear pore of human cervical carcinoma HeLa and SiHa cells
생화학적/생리학적 작용
Lectin from Triticum vulgaris (wheat) possessing four binding sites is specific for N-acetyl-d-glucosamine and N-acetyl-d-neuraminic acid (sialic acid) residues. Lectins also function as a fungicide. They also possess anti-nutritive effects.
WGA is not blood group specific but has an affinity for N-acetyl-β-D-glucosaminyl residues and N-acetyl-β-D-glucosamine oligomers. WGA contains no protein-bound carbohydrate.
제조 메모
Conjugates are prepared from affinity purified lectin.
기타 정보
Highly purified
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
Plant lectins: occurrence, biochemistry, functions and applications
Rudiger H and Gabius HJ
Glycoconjugate Journal, 18, 589-613 (2001)
Tsung-Lin Tsai et al.
International journal of nanomedicine, 7, 5215-5234 (2012-10-17)
Gold nanoparticles modified with the nuclear localization signal from simian virus 40 large T antigen (GNP-PEG/SV40) accumulate on the cytoplasmic side of the nuclear membrane in HeLa cells. Accumulation of GNP-PEG/SV40 around the nucleus blocks nucleocytoplasmic transport and prevents RNA
Nuclear localization of Tob is important for regulation of its antiproliferative activity
Kawamura-Tsuzuku J, et al.
Oncogene, 23, 6630-6630 (2004)
Effects of wheat germ agglutinin on human gastrointestinal epithelium: insights from an experimental model of immune/epithelial cell interaction
Dalla P, et al.
Toxicology and Applied Pharmacology, 237, 146-153 (2009)
Super-multiplex vibrational imaging
Wei L, et al.
Nature, 544, 465-465 (2017)
문서
Find the right lectin for your research with our lectin selection guide, organized by lectin source/species, carbohydrate specificity, blood group specificity, and more.
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