I1020
IL-4 mouse
≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
동의어(들):
Interleukin-4, mIL-4, Interleukin-4 human
제품 이름
Interleukin-4 from mouse, IL-4, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
생물학적 소스
mouse
재조합
expressed in E. coli
분석
≥98% (SDS-PAGE)
양식
lyophilized powder
효능
0.1-2.0 ng/mL ED50/EC50
품질
endotoxin tested
분자량
~13.5 kDa
포장
pkg of 5 μg
기술
cell culture | mammalian: suitable
불순물
<0.1 EU/μg
UniProt 수납 번호
저장 온도
−20°C
유전자 정보
mouse ... Il4(16189)
애플리케이션
Interleukin-4 from mouse has been used:
- as a component of cell culture media for class switch recombination assay
- to study its therapeutic benefits for mucosal healing
- as a pioglitazone or new peroxisome proliferator-activated receptor agonist (GQ-11)
생화학적/생리학적 작용
Interleukin-4 (IL-4) is a lymphokine with profound effects on the growth and differentiation of immunologically competent cells. IL-4 is also known as B cell stimulatory factor-1 (BSF-1), T cell growth factor-2 (TCGF-2) and mast-cell growth factor-2 (MCGF-2). Inhibits VEGF-induced and FGF-Basic-induced angiogenesis. IL-4 is a complex glycoprotein released by a subset of activated T cells. Treatment of IL-4 with specific glycosidases yields an active polypeptide. Human and mouse IL-4 share 50% amino acid sequence homology, but their biological actions are species-specific.
Interleukin-4, a lymphokine with profound effects on the growth and differentiation of immunologically competent cells, inhibits VEGF-induced and bFGF-induced angiogenesis. Human and mouse IL-4 share 50% amino acid sequence identity, but their biological actions are species-specific.
물리적 형태
Lyophilized, 0.2 μm filtered, with no additives.
분석 메모
The proliferative activity is tested in culture using mouse HT-2 cells.
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
R Fernandez-Botran et al.
The Journal of experimental medicine, 164(2), 580-593 (1986-08-01)
T cell-derived supernatants (SN) that contain B cell-stimulatory factor 1 (BSF-1) and lack IL-2 promote the growth of the IL-2-dependent T cell line, HT-2, as well as three other clones or lines of T cells that can provide help to
Jun-ichi Shono et al.
Animal science journal = Nihon chikusan Gakkaiho, 84(11), 744-750 (2013-08-29)
Muscle damage induces massive macrophage infiltration of the injury site, in which activated pro-inflammatory and anti-inflammatory phenotypes (currently classified as M1 and M2, respectively) have been documented as distinct functional populations predominant at different times after the conventional acute injury
New Peroxisome Proliferator-Activated Receptor Agonist (GQ-11) Improves Wound Healing in Diabetic Mice
Silva JC, et al.
Advances in Wound Care (2019)
Interleukin 4 induces rapid mucin transport, increases mucus thickness and quality and decreases colitis and Citrobacter rodentium in contact with epithelial cells
Sharba S, et al.
Virulence, 10(1), 97-117 (2019)
VX-984 is a selective inhibitor of non-homologous end joining, with possible preferential activity in transformed cells
Khan AJ, et al.
Oncotarget, 9(40), 25833-25833 (2018)
문서
Interleukins, released from leukocytes, include IL-1β playing crucial roles in inflammation, immune responses, and anti-tumor immunity.
관련 콘텐츠
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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