G4796

Genipin

Name: Genipin
Brand: SIGMA

≥98% (HPLC), powder, insulin stimulator

동의어(들):

Methyl (1S,2R,6S)-2-hydroxy-9-(hydroxymethyl)-3-oxabicyclo[4.3.0]nona-4,8-diene-5-carboxylate

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):

C₁₁H₁₄O₅

CAS 번호:

6902-77-8

Molecular Weight:

226.23

MDL number:

MFCD00888600

UNSPSC 코드:

12352200

PubChem Substance ID:

329799931

NACRES:

NA.77

주요 문서

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제품 이름

Genipin, ≥98% (HPLC), powder

Quality Level

100

분석

≥98% (HPLC)

양식

powder

solubility

DMSO: ≥25 mg/mL
H₂O: insoluble

SMILES string

COC(=O)C1=CO[C@@H](O)C2C1CC=C2CO

InChI

1S/C11H14O5/c1-15-10(13)8-5-16-11(14)9-6(4-12)2-3-7(8)9/h2,5,7,9,11-12,14H,3-4H2,1H3/t7-,9-,11-/m1/s1

InChI key

AZKVWQKMDGGDSV-BCMRRPTOSA-N

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일반 설명

Genipin is a natural cross linking agent, which is extracted from gardenia fruit. It prevents lipid peroxidation and production of nitric oxide. Genipin protects the hippocampal neurons from the toxicity of Alzheimer′s amyloid β protein. It has anti-inflammatory and anti-angiogenesis effects. Genipin is involved in drug delivery system.

애플리케이션

Genipin has been used:

in chemosensitivity assay
in the preparation of recombinant human (rh)-odontogenic ameloblast-associated protein (ODAM) -impregnated collagen gel and in vitro mineralization assay
in genipin gel preparation

생화학적/생리학적 작용

Genipin stimulates insulin secretion in UCP2-dependent manner (Uncoupling protein 2).

Genipin stimulates insulin secretion in UCP2-dependent manner (Uncoupling protein 2). Genipin is a protein, collagen, gelatin, and chitosan cross-linker.

특징 및 장점

This compound is featured on the InsR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

픽토그램

GHS06

신호어

Danger

유해 및 위험 성명서

H301

예방조치 성명서

P264 - P270 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Using dairy ingredients to produce edible films and biodegradable packaging materials

Tomasula PM

Dairy-Derived Ingredients: Food and Nutraceutical Uses, 589-624 (2009)

Genipin-crosslinked chitosan hydrogels as biomedical and pharmaceutical aids

Muzzarelli RAA

Carbohydrate Polymers, 77(1), 1-9 (2009)

Astrocyte infiltration into injectable collagen-based hydrogels containing FGF-2 to treat spinal cord injury.

Daniel J Macaya et al.

Biomaterials, 34(14), 3591-3602 (2013-02-19)

Astrocytes can play dual roles in the response to spinal cord injury (SCI) acting as both an inhibitory barrier and a trophic support for growth axons. Therefore, migration of these cells into the defect as opposed to forming a scar

In vitro cytocompatibility evaluation of alginate dialdehyde for biological tissue fixation.

Yuanting Xu et al.

Carbohydrate polymers, 92(1), 448-454 (2012-12-12)

Biological tissues must be chemically fixed before they can be implanted in humans, due to the immediate degradation and presence of antigenicity of naturally derived tissues. To provide a crosslinking reagent which is cytocompatible and may prepare biocompatible fixed tissues

Biocompatible fibrous networks of cellulose nanofibres and collagen crosslinked using genipin: potential as artificial ligament/tendons.

Aji P Mathew et al.

Macromolecular bioscience, 13(3), 289-298 (2012-12-12)

Bio-based fibrous nanocomposites of cellulose nanofibres and non-crosslinked/crosslinked collagen were prepared by in situ pH-induced fibrillation of collagen phase and sterilized using gamma rays at 25 KGy. Collagen phase is crosslinked using genipin, a bio-based crosslinker that introduces flexible crosslinks.

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Genipin

≥98% (HPLC), powder, insulin stimulator

크기 선택

제품정보 (DICE 배송 시 비용 별도)

주요 문서

속성

제품 이름

Quality Level

분석

양식

solubility

SMILES string

InChI

InChI key

관련 카테고리

설명

일반 설명

애플리케이션

생화학적/생리학적 작용

특징 및 장점

안전성 정보

픽토그램

신호어

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Storage Class Code

WGK

Flash Point (°F)

Flash Point (°C)

개인 보호 장비

문서

시험 성적서(COA)

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