C8754
Thiamine pyrophosphate
≥95%, powder
동의어(들):
Aneurinepyrophosphoric acid, Cocarboxylase, Thiamine pyrophosphate chloride
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C12H19ClN4O7P2S
CAS 번호:
Molecular Weight:
460.77
Beilstein:
3875902
EC Number:
MDL number:
UNSPSC 코드:
12352204
PubChem Substance ID:
NACRES:
NA.54
제품 이름
Thiamine pyrophosphate, ≥95%
Quality Level
분석
≥95%
양식
powder
solubility
H2O: soluble 50 mg/mL, clear to very slightly hazy, colorless
저장 온도
−20°C
SMILES string
CC1=C(CCOP(OP(O)(O)=O)(O)=O)SC=[N+]1CC2=C(N)N=C(C)N=C2.[Cl-]
InChI
1S/C12H18N4O7P2S.ClH/c1-8-11(3-4-22-25(20,21)23-24(17,18)19)26-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7H,3-4,6H2,1-2H3,(H4-,13,14,15,17,18,19,20,21);1H
InChI key
YXVCLPJQTZXJLH-UHFFFAOYSA-N
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관련 카테고리
애플리케이션
Thiamine pyrophosphate from Sigma has been used as a substrate to assay the enzymes in golgi lamellae isolated from rat tissue.
Thiamine pyrophosphate has been used:
- for the preparation of chitosan nano-particles
- as a standard for vitamin B1 and its derivative in high-performance
- liquid chromatography (HPLC) analysis
- immunofluorescence
생화학적/생리학적 작용
Thiamine pyrophosphate (TPP) is a coenzyme of transketolase, that catalyzes the cleavage of ribulose-5-phosphate. This reaction leads to the formation of D-glyceraldehyde-3-phosphate. It requires the addition of an acceptor aldehyde such as ribose-5-phosphate, glyceraldehye or glycolaldehyde. TPP is capable of decarboxylating hydroxypyruvate in the presence of an ′acceptor aldehyde′.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Skin Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
Immunofluorescence Analysis of Human Endocervical Tissue Explants Infected with Neisseria gonorrhoeae
Wang LC, et al.
Bio-protocol, 8(3) (2018)
Effects of anti-CD44 monoclonal antibody IM7 carried with chitosan polylactic acid-coated nano-particles on the treatment of ovarian cancer
Yang Y, et al.
Oncology Letters, 13(1), 99-104 (2017)
Nucleosidediphosphatase activity in the Golgi apparatus and its usefulness for cytological studies.
A B NOVIKOFF et al.
Proceedings of the National Academy of Sciences of the United States of America, 47, 802-810 (1961-06-15)
Thiamine pyrophosphate, a coenzyme of transketolase
Racker E, et al.
Journal of the American Chemical Society, 75(4), 1010-1011 (1953)
Sanshu Li et al.
Nucleic acids research, 41(5), 3022-3031 (2013-02-05)
Thiamin pyrophosphate (TPP) riboswitches are found in organisms from all three domains of life. Examples in bacteria commonly repress gene expression by terminating transcription or by blocking ribosome binding, whereas most eukaryotic TPP riboswitches are predicted to regulate gene expression
문서
Explore thiamine's impact on serum-free cell culture systems for biomanufacturing monoclonal antibodies.
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