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M9771

N-Methoxysuccinyl-Ala-Ala-Pro-Val-7-amido-4-methylcoumarin

Name: N-Methoxysuccinyl-Ala-Ala-Pro-Val-7-amido-4-methylcoumarin
Brand: SIGMA

elastase substrate

동의어(들):

MeOSuc-AAPV-AMC

조직 및 계약 가격을 보려면 로그인를 클릭합니다.

크기 선택

보기 변경

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):

C₃₁H₄₁N₅O₉

CAS 번호:

72252-90-5

Molecular Weight:

627.69

NACRES:

NA.32

PubChem Substance ID:

24897367

UNSPSC Code:

12352204

MDL number:

MFCD00077135

기술 서비스

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도움 문의

속성

Quality Level

200

assay

≥98% (HPLC)

form

powder

solubility

chloroform: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

COC(=O)CCC(=O)NC(C)C(=O)NC(C)C(=O)N1CCCC1C(=O)NC(C(C)C)C(=O)Nc2ccc3C(C)=CC(=O)Oc3c2

InChI

1S/C31H41N5O9/c1-16(2)27(30(42)34-20-9-10-21-17(3)14-26(39)45-23(21)15-20)35-29(41)22-8-7-13-36(22)31(43)19(5)33-28(40)18(4)32-24(37)11-12-25(38)44-6/h9-10,14-16,18-19,22,27H,7-8,11-13H2,1-6H3,(H,32,37)(H,33,40)(H,34,42)(H,35,41)

InChI key

CMEUDEVBFFPSEI-UHFFFAOYSA-N

설명

General description

Fluorogenic substrate for the assay of human leukocyte and porcine pancreatic elastase.

Application

N-Methoxysuccinyl-Ala-Ala-Pro-Val-7-amido-4-methylcoumarin has been used as a substrate in elastase assay using bone marrow lysates and pancreatic lysates.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Sensitive substrates for human leukocyte and porcine pancreatic elastase: a study of the merits of various chromophoric and fluorogenic leaving groups in assays for serine proteases.

M J Castillo et al.

Analytical biochemistry, 99(1), 53-64 (1979-10-15)

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Jonas Hahn et al.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(1), 1401-1414 (2018-08-22)

Papillon-Lefèvre syndrome (PLS) is characterized by nonfunctional neutrophil serine proteases (NSPs) and fulminant periodontal inflammation of unknown cause. Here we investigated neutrophil extracellular trap (NET)-associated aggregation and cytokine/chemokine-release/degradation by normal and NSP-deficient human and mouse granulocytes. Stimulated with solid or

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국제 무역 품목 번호

SKU	GTIN
M9771-5MG	04061832909486
M9771-50MG	04061832909479