L7386
Lysostaphin from Staphylococcus staphylolyticus
≥500 units/mg protein, lyophilized powder
동의어(들):
Glycyl-glycine Endopeptidase
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크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
CAS 번호:
UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
제품 이름
Lysostaphin from Staphylococcus staphylolyticus, lyophilized powder, Protein 50-70 % by biuret, ≥500 units/mg protein
biological source
microbial (Staphylococcus staphylotyticus)
Quality Level
form
lyophilized powder
specific activity
≥500 units/mg protein
mol wt
25 kDa
composition
Protein, 50-70% biuret
packaging
pkg of (sold on basis of mg protein)
solubility
water: 2.00-2.10 mg/mL, clear to slightly hazy, colorless to light yellow
antibiotic activity spectrum
Gram-positive bacteria
application(s)
diagnostic assay manufacturing
mode of action
cell wall synthesis | interferes
shipped in
wet ice
storage temp.
−20°C
General description
Chemical structure: peptide
Biochem/physiol Actions
Lysostaphin is a zinc endopeptidase with a molecular weight of approximately 25 kDa. Because lysostaphin cleaves the polyglycine cross-links in the peptidoglycan layer of the cell wall of Staphylococcus species it has been found useful for cell lysis and also as a potential anti-microbial therapeutic.
pH Optimum for activity: ~7.5
pH Optimum for activity: ~7.5
Other Notes
One unit will reduce the turbidity (A620) of a suspension of Staphylococcus aureus cells from 0.250 to 0.125 in 10 min at pH 7.5 at 37°C in a 6.0 ml reaction mixture.
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
프로토콜
GenElute™ Bacterial Genomic DNA Kit protocol describes a simple and convenient way for the isolation of pure genomic DNA from bacteria.
Lisbeth Drozd Lund et al.
PloS one, 11(2), e0149092-e0149092 (2016-02-13)
Staphylococcus aureus is a major human pathogen that has evolved very efficient immune evading strategies leading to persistent colonization. During different stages of growth, S. aureus express various surface molecules, which may affect the immune stimulating properties, but very little
Ian R Monk et al.
Nature communications, 10(1), 3067-3067 (2019-07-13)
WalKR (YycFG) is the only essential two-component regulator in the human pathogen Staphylococcus aureus. WalKR regulates peptidoglycan synthesis, but this function alone does not explain its essentiality. Here, to further understand WalKR function, we investigate a suppressor mutant that arose
Judy J J Ou et al.
Frontiers in cellular and infection microbiology, 6, 187-187 (2017-01-14)
Background:Staphylococcus aureus (S. aureus) small colony variants (SCVs) can survive within the host intracellular milieu and are associated with chronic relapsing infections. However, it is unknown whether host invasion rates and immune responses differ between SCVs and their wild-type counterparts.
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| L7386-15MG | 04061838446329 |
| L7386-1MG | 04061838446336 |
| L7386-500MG | 04061831159530 |
| L7386-5MG | 04061838446343 |