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L1012

Linoleic acid

Name: Linoleic acid
Brand: SIGMA

liquid, BioReagent, suitable for cell culture

동의어(들):

cis-9,cis-12-Octadecadienoic acid

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:

CH₃(CH₂)₄CH=CHCH₂CH=CH(CH₂)₇CO₂H

CAS 번호:

60-33-3

Molecular Weight:

280.45

NACRES:

NA.75

PubChem Substance ID:

24896270

eCl@ss:

32190102

UNSPSC Code:

12352211

EC Number:

200-470-9

MDL number:

MFCD00064241

Beilstein/REAXYS Number:

1727101

기술 서비스

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도움 문의

속성

biological source

plant (Safflower oil)

Quality Level

200

product line

BioReagent

assay

≥98%

form

liquid

technique(s)

cell culture | mammalian: suitable

refractive index

n20/D 1.466 (lit.)

bp

229-230 °C/16 mmHg (lit.)

mp

−5 °C (lit.)

solubility

NaOH: 1 M, ethanol: soluble

density

0.902 g/mL at 25 °C (lit.)

storage temp.

−20°C

SMILES string

OC(CCCCCCC/C=C\C/C=C\CCCCC)=O

InChI

1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9-

InChI key

OYHQOLUKZRVURQ-HZJYTTRNSA-N

Gene Information

human ... SOAT1(6646), SOAT2(8435)

설명

General description

Linoleic acid (LA) is the precursor for the synthesis of arachidonic prostaglandins and other eicosanoids. LA is present in vegetable oils and meat.

Application

Linoleic acid has been used as a component of S12 medium for cardiomyocytes differentiation, minimum essential medium α for spermatogonial stem cell culture and for endothelial differentiation of mouse adipose-derived stem cells (mASC).

Fatty acid that is typically bound to a carrier molecule such as BSA or cyclodextrin for use in cell culture.

Biochem/physiol Actions

Linoleic acid increases cell proliferation and gene expression of PPARα and its target genes such as acyl-CoA oxidase in primary duck hepatocytes .

Linoleic acid (LA) may improve wound healing in diabetic rat. The levels of LA in adipose tissue and platelets are correlated with coronary artery disease. It may induce tumor and apoptosis in colorectal cancer cells. Studies also support their protective effects in lymphocytes. Linoleic acid is typically bound to a carrier molecule such as bovine serum albumin (BSA) or cyclodextrin for use in cell culture.

Packaging

Sealed ampule.

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저장 등급

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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문서

Lipid-induced Insulin Resistance

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국제 무역 품목 번호

SKU	GTIN
L1012-5G	04061833949160
L1012-100MG	04061833949146
L1012-1G	04061833949153