EX-CELL^® Advanced CHO Fed-batch Medium

EX-CELL^® AdvancedCHO Fed-batch Medium is chemically-defined and contains no animal derived components. This newest platform from SAFC has been specifically developed to support growth and productivity across a diverse set of Chinese Hamster Ovary (CHO) cells in fed-batch cultures while still allowing for flexibility in the adjustment of protein quality attributes. This contemporary fed-batch platform was developed using a strategy of Multivariate Analysis to establish correlations in which the formulation components influence critical process and product attributes such as titer, fold expansion, receptor expression, and glycosylation. This platform contains no hypoxanthine and thymidine, L-glutamine, phenol red or 2-mercaptoethanol (2-ME). This medium is intended to be a part of a fed-batch platform, and used with EX-CELL^® Advanced CHO Feed 1 (24367C - with glucose or 24368C - without glucose).

Formulated to contain 22.09 grams of powder per liter of medium.

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany