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Merck

PHR1503

Supelco

Cilostazol

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

Cilostazol, 6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-2(1H)-quinolinone, OPC 13013, OPC 21, Pletaal

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C20H27N5O2
CAS 번호:
73963-72-1
Molecular Weight:
369.46
MDL number:
MFCD00866780
UNSPSC 코드:
41116107
PubChem Substance ID:
329823424
NACRES:
NA.24

주요 문서

모든 문서 보기
기술 서비스
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도움 문의
기술 서비스
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도움 문의

Grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to USP 1134153

API family

cilostazol

CofA

current certificate can be downloaded

포장

package of 1 g

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

pharmaceutical (small molecule)

형식

neat

저장 온도

2-30°C

SMILES string

O=C1CCc2cc(OCCCCc3nnnn3C4CCCCC4)ccc2N1

InChI

1S/C20H27N5O2/c26-20-12-9-15-14-17(10-11-18(15)21-20)27-13-5-4-8-19-22-23-24-25(19)16-6-2-1-3-7-16/h10-11,14,16H,1-9,12-13H2,(H,21,26)

InChI key

RRGUKTPIGVIEKM-UHFFFAOYSA-N

유전자 정보

human ... PDE3A(5139)

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관련 카테고리

일반 설명

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Cilostazol is a dihydro-quinolinone derivative, that is predominantly used as an anti-platelet and vasodilatory agent. It acts by inhibition of cyclic adenosine monophosphate (cAMP) phosphodiesterase, which results in elevation of cAMP levels in platelets and blood vessels, thus inhibiting platelets aggregation.

애플리케이션

Cilostazol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

분석 메모

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

기타 정보

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA3090 in the slot below. This is an example certificate only and may not be the lot that you receive.

픽토그램

Health hazard
GHS08

신호어

Warning

유해 및 위험 성명서

H361d

Hazard Classifications

Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

HPLC determination of cilostazol in tablets, and its validation
Lestari AD, et al.
Journal of Liquid Chromatography and Related Technologies, 27(16), 2603-2612 (2004)
Cilostazol (Pletal ?): a dual inhibitor of cyclic nucleotide phosphodiesterase type 3 and adenosine uptake
Liu YS, et al.
Cardiovascular Drug Reviews, 19(4), 369-386 (2001)
Validated stability-indicating methods for determination of cilostazol in the presence of its degradation products according to the ICH guidelines
Fayed AS, et al.
Journal of Pharmaceutical and Biomedical Analysis, 45(3), 407-416 (2007)

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