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Merck

PHR1380

Supelco

Ivermectin

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

Ivermectin, 22,23-Dihydroavermectin B1, MK-933

로그인조직 및 계약 가격 보기

크기 선택

제품정보 (DICE 배송 시 비용 별도)

CAS 번호:
70288-86-7
EC Number:
274-536-0
MDL number:
MFCD00869511
UNSPSC 코드:
41116107
PubChem Substance ID:
329823357
NACRES:
NA.24

주요 문서

모든 문서 보기
기술 서비스
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도움 문의
기술 서비스
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도움 문의

Grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

USP 1354309
traceable to Ph. Eur. I8000010

API family

ivermectin

CofA

current certificate can be downloaded

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

pharmaceutical (small molecule)

형식

neat

저장 온도

2-8°C

SMILES string

[H][C@@]1(O[C@]2(CC[C@@H]1C)C[C@@H]3C[C@@H](C\C=C(C)\[C@@H](O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)\C=C\C=C6/CO[C@]7([H])[C@H](O)C(C)=C[C@@H](C(=O)O3)[C@]67O)O2)[C@@H](C)CC

InChI

1S/C48H74O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,19,25-26,28,30-31,33-45,49-50,52H,11,16-18,20-24H2,1-10H3/b13-12+,27-15+,32-14+/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1

InChI key

AZSNMRSAGSSBNP-XPNPUAGNSA-N

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관련 카테고리

일반 설명

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Ivermectin is a derivative of avermectin B1 that is used against both endo- and ectoparasites in veterinary applications. It has also been indicated as a potential drug for the management of Onchocerca volvulus, identified as the cause of ′river blindness′ in humans.

애플리케이션

Ivermectin may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and plasma samples by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

분석 메모

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

기타 정보

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA1636 in the slot below. This is an example certificate only and may not be the lot that you receive.

픽토그램

Skull and crossbonesEnvironment
GHS06,GHS09

신호어

Danger

유해 및 위험 성명서

H300,H311,H410

Hazard Classifications

Acute Tox. 1 Oral - Acute Tox. 3 Dermal - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Ivermectin disposition kinetics after subcutaneous and intramuscular administration of an oil-based formulation to cattle
Lifschitz A, et al.
Veterinary Parasitology, 86(3), 203-215 (1999)
Ivermectin (3.15%) long-acting formulations in cattle: absorption pattern and pharmacokinetic considerations
Lifschitz A, et al.
Veterinary Parasitology, 147(3-4), 303-310 (2007)
Liquid chromatographic determination of ivermectin in animal plasma with trifluoroacetic anhydride and N-methylimidazole as the derivatization reagent
de Montigny P, et al.
Journal of Pharmaceutical and Biomedical Analysis, 8(6), 507-511 (1990)
Feng Xiong et al.
The Plant cell, 32(12), 3812-3824 (2020-09-30)
Plant roots are sustained through meristem activity at the root tip. Two transcriptional pathways, one mediated by PLETHORAs (PLTs) and the other by SHORTROOT and SCARECROW, play major roles in root meristem development. The role of PLTs during root meristem

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