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Merck

PHR1340

Supelco

Pyrilamine maleate

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

Pyrilamine maleate salt, Mepyramine maleate salt, N-(4-Methoxyphenyl)methyl-N′,N′-dimethyl-N-(2-pyridinyl)-1,2-ethanediamine maleate salt

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C17H23N3O · C4H4O4
CAS 번호:
59-33-6
Molecular Weight:
401.46
EC Number:
200-422-7
MDL number:
MFCD00069333
UNSPSC 코드:
41116107
PubChem Substance ID:
329823325
NACRES:
NA.24

주요 문서

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기술 서비스
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도움 문의
기술 서비스
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도움 문의

Grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to Ph. Eur. M0500000
traceable to USP 1588004

API family

mepyramine, pyrilamine

CofA

current certificate can be downloaded

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

pharmaceutical (small molecule)

형식

neat

저장 온도

2-30°C

SMILES string

OC(=O)\C=C/C(O)=O.COc1ccc(CN(CCN(C)C)c2ccccn2)cc1

InChI

1S/C17H23N3O.C4H4O4/c1-19(2)12-13-20(17-6-4-5-11-18-17)14-15-7-9-16(21-3)10-8-15;5-3(6)1-2-4(7)8/h4-11H,12-14H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

JXYWFNAQESKDNC-BTJKTKAUSA-N

유전자 정보

human ... HRH1(3269)

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관련 카테고리

일반 설명

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pyrilamine maleate is a first generation antihistamine drug, widely used to reduce all symptoms of cold and is also employed to reduce allergies both parenterally and locally.

애플리케이션

Pyrilamine maleate may be used pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using high-performance liquid chromatography technique and liquid chromatography technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

분석 메모

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

기타 정보

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA1092 in the slot below. This is an example certificate only and may not be the lot that you receive.

픽토그램

Exclamation mark
GHS07

신호어

Warning

유해 및 위험 성명서

H302,H315,H319,H335

예방조치 성명서

P261 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Trace analysis of the antihistamines methapyrilene hydrochloride, pyrilamine maleate and triprolidine hydrochloride monohydrate in animal feed, human urine and wastewater by high-performance liquid chromatography and gas chromatography with nitrogen?phosphorus detection.
Thompson C H and Holder L C.
Journal of Chromatography A, 283, 251-264 (1984)
Simultaneous determination of dextromethorphan hydrobromide, pyrilamine maleate and sodium benzoate in a cough cold syrup by LC
Louhaichi RM, et al.
Chromatographia, 69(5), 421-427 (2009)
Simultaneous determination of acetaminophen, pamabrom and pyrilamine maleate in pharmaceutical formulations using stability indicating HPLC assay method
Saleem A, et al.
Journal of the Mexican Chemical Society, 59(2), 93-98 (2015)
Validation of a HPLC quantification of acetaminophen, phenylephrine and chlorpheniramine in pharmaceutical formulations: capsules and sachets.
Marin A, et al.
Journal of Pharmaceutical and Biomedical Analysis, 29(4), 701-714 (2002)
Lingli Yang et al.
The Journal of investigative dermatology, 134(8), 2105-2113 (2014-03-01)
Histamine is thought to have a critical role in the synthesis of extracellular matrix in skin and may be involved in tissue remodeling of allergic diseases. Recent studies revealed that periostin, a matricelluar protein, contributed to tissue remodeling; however, a
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